The BEST episodes of Grey's Anatomy season 21

Every episode of Grey's Anatomy season 21, ranked from best to worst by thousands of votes from fans of the show. The best episodes of Grey's Anatomy season 21!

A drama centered on the personal and professional lives of five surgical interns and their supervisors.

Last Updated: 11/15/2024Network: ABC (US)Status: Continuing
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If You Leave
star
7.78
18 votes

#1 - If You Leave

Season 21 - Episode 7 - Aired 11/14/2024

The doctors at Grey Sloan must put aside their emotions under intense circumstances. Levi asks James a shocking question that could impact their future.

Watch Now:AmazonApple TV
Night Moves
star
7.66
143 votes

#2 - Night Moves

Season 21 - Episode 6 - Aired 11/7/2024

Teddy and Owen plan a date night that gets derailed in more ways than one, while Jo struggles to do it all at home. Mika adds more to her plate to make up for taking time off to be with her sister, and Levi is faced with a monumental decision.

Directors: Bille Woodruff
Watch Now:Apple TV
I Can See Clearly Now
star
7.46
224 votes

#3 - I Can See Clearly Now

Season 21 - Episode 3 - Aired 10/10/2024

Simone and Lucas work to balance their relationship while competing to assist on an awake kidney transplant. Teddy offers Amelia a new opportunity, and Ben’s interview doesn’t go as planned. Meredith’s secret causes tension with Richard.

Directors: Victoria Mahoney
Watch Now:Apple TV
This One's for the Girls
star
7.45
201 votes

#4 - This One's for the Girls

Season 21 - Episode 4 - Aired 10/17/2024

Mika struggles with a life-altering personal matter. Meanwhile, Bailey and Ben navigate their personal and professional roles, while Levi finds a connection in an unlikely place. Jo and Link get surprising news.

Directors: Debbie Allen
Watch Now:Apple TV
If Walls Could Talk
star
7.36
251 votes

#5 - If Walls Could Talk

Season 21 - Episode 1 - Aired 9/26/2024

After firing some of Grey Sloan’s best, Catherine continues to interfere with Meredith and Amelia’s research. Accidents at a climate change protest bring unique cases to the hospital, and Bailey encounters a blast from the past.

Directors: Debbie Allen
Writer: Meg Marinis
Watch Now:Apple TV
Take Me to Church
star
7.33
232 votes

#6 - Take Me to Church

Season 21 - Episode 2 - Aired 10/3/2024

Meredith and Catherine continue to disagree, and Meredith confides in Bailey for support. Richard, Winston and Lucas spend the day outside of the hospital, and Blue deals with a relationship from his past. Levi meets the new hospital chaplain.

Directors: Kevin McKidd
Watch Now:Apple TV
You Make My Heart Explode
star
7.32
189 votes

#7 - You Make My Heart Explode

Season 21 - Episode 5 - Aired 10/24/2024

During a high-stress day at Grey Sloan Memorial, the fates of a patient in critical condition and a helicopter-bound medical team hang in the balance. Beltran spearheads an initiative, Teddy and Owen work on their marriage, while Bailey, Blue and Link treat a hospital employee.

Directors: Vanessa Parise
Writer: Zoanne Clack
Watch Now:Apple TV