The BEST episodes of Heartbeat (2016)

Every episode of Heartbeat (2016) ever, ranked from best to worst by thousands of votes from fans of the show. The best episodes of Heartbeat (2016)!

Based on the real life and achievements of Dr. Kathy Magliato, this unique character-driven medical drama follows Dr. Alex Panttiere, an outspoken, world-renowned heart transplant surgeon, one of the few women in her field. Stubborn and fearless, Alex always operates on her own terms. She revels in a racy personal life that's a full-time job in itself, manages the daily demands of skeptical faculty and dutiful interns, and pushes the boundaries of medical science to impressive new heights.

Last Updated: 9/25/2023Network: NBCStatus: Ended
What Happens in Vegas... Happens
202 votes

#1 - What Happens in Vegas... Happens

Season 1 - Episode 10 - Aired 5/25/2016

Alex fights to save the lives of Jesse, Pierce and Ji-Sung when a mysterious and deadly illness sends the hospital into lockdown. Meanwhile, Millicent must pick up the pieces when Alex disobeys the orders of the CDC, and an elderly man searching for his missing wife leads Alex to make a drastic decision in her love life.

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The Inverse
257 votes

#2 - The Inverse

Season 1 - Episode 6 - Aired 4/27/2016

A case brings back memories for Alex, Jesse and Millicent as they fight to save a heart transplant patient when she sustains devastating injuries in a car crash.

Directors: Liz Friedlander
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100,000 Heartbeats
287 votes

#3 - 100,000 Heartbeats

Season 1 - Episode 4 - Aired 4/6/2016

Alex and Pierce disagree on whether an experimental treatment for those with advanced stage cancer is right for the hospital's patients. True to form, Alex takes matters into her own hands with a risky move to find volunteers. Meanwhile, Max looks to drastically change the family dynamic with Alex, and Ji-Sung connects with Callahan.

Directors: Helen Shaver
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Permanent Glitter
254 votes

#4 - Permanent Glitter

Season 1 - Episode 7 - Aired 5/4/2016

Alex and Ji-Sung fight to save the life of a transgender woman with breast cancer; a consultant from another hospital forces Jesse to confront her feelings for Alex.

Writer: Mike Lyons
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The Land of Normal
275 votes

#5 - The Land of Normal

Season 1 - Episode 5 - Aired 4/20/2016

A patient questions Alex's ability to leave personal grief outside the OR when she performs heart surgery on the anniversary of her sister's death; Millicent dates an artist; Pierce wants to be more of a part of Alex's family.

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200 votes

#6 - Sanctuary

Season 1 - Episode 9 - Aired 5/18/2016

Alex tries to fulfill the dying wish of a young heart patient.

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337 votes

#7 - Backwards

Season 1 - Episode 3 - Aired 3/30/2016

When a young man is only able to speak sentences backwards, Alex sees this as the perfect opportunity to test out some new technology. While Jesse agrees this is the best course of action, Millicent believes otherwise. This tension within their department might stem from past history which could further complicate things between Alex and Pierce.

Directors: Reginald Hudlin
Writer: Jill Gordon
Watch Now:AmazonApple TV
Match Game
247 votes

#8 - Match Game

Season 1 - Episode 8 - Aired 5/11/2016

When Alex's father needs a new kidney, an unlikely donor emerges and family secrets threaten to destroy the close relationship between father and daughter.

Directors: Edward Ornelas
Writer: Cindy Appel
Watch Now:AmazonApple TV
329 votes

#9 - Twins

Season 1 - Episode 2 - Aired 3/23/2016

When conjoined twins arrive at the hospital with a cancer diagnoses, Alex recommends a very risky surgery, resulting in a major ethical debate within the department. After spending time with the twins and observing their unique relationship, Alex also begins to question her relationship with Pierce.

Writer: Jill Gordon
Watch Now:AmazonApple TV
405 votes

#10 - Pilot

Season 1 - Episode 1 - Aired 3/22/2016

When a new patient is in desperate need of a heart transplant, we are introduced to the life of world-renowned heart transplant surgeon Dr. Alexandra Panttiere. There is nothing conventional about Alex. She is as cutting edge and unorthodox in the OR as she is with the two men in her life. Her approach to medicine is without boundaries, as is her approach to everything else in her world, which is always full of surprises.

Writer: Jill Gordon
Watch Now:AmazonApple TV