The Best Episodes of Grey's Anatomy

Last Updated: Nov 26, 2018

A drama centered on the personal and professional lives of five surgical interns and their supervisors.

Death and All His Friends

#1 - Death and All His Friends

Season 6 - Episode 24

Cristina and Meredith's surgical skills are put to the ultimate test.

star 8.55
781 votes
Directors: Rob Corn
Writers: Shonda Rhimes
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Losing My Religion (2)

#2 - Losing My Religion (2)

Season 2 - Episode 27

This episode is the second part of a two-hour season finale. Richard tries to get information from Addison about a family member's condition. Callie and George have a talk about his feelings. Meredith and Derek have a talk about Doc.

star 8.51
612 votes
Directors: Mark Tinker
Writers: Shonda Rhimes
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Now or Never

#3 - Now or Never

Season 5 - Episode 24

In the second part of the two hour season finale, George delivers stunning news to Bailey, sending shockwaves throughout the hospital, and Izzie's friends anxiously await her recovery from surgery. Meanwhile Bailey is surprisingly displeased after being accepted into the pediatric fellowship program, and the victim of a near-fatal traffic accident brings the talents of Seattle Grace's doctors together. This is the second hour of a 2-hour season finale.

star 8.47
680 votes
Directors: Rob Corn
Writers: Debora Cahn
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As We Know it

#4 - As We Know it

Season 2 - Episode 17

Derek is still operating when he finds out about Meredith's current situation. Meredith is freaking out about her situation. Webber and Bailey are dealing with medical health issues. Cristina and Izzie have their own issues to deal with because of Meredith's situation. Addison freaks out when George tries to find a solution to Bailey's impromtu postponement. Overall, Seattle Grace Hospital is still under code black and the situation is getting worse.

star 8.45
773 votes
Directors: Peter Horton
Writers: Shonda Rhimes
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Perfect Storm

#5 - Perfect Storm

Season 9 - Episode 24

Grey Sloan Memorial Hospital enters crisis mode as the storm rages, resources become scarce and patients flood in by the busload. Meanwhile, one of the doctors fights for their life.

star 8.42
1,007 votes
Directors: Rob Corn
Writers: Stacy McKee
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It's the End of the World

#6 - It's the End of the World

Season 2 - Episode 16

An explosive case arrives at the O.R. that might endanger all the lives of the people working there, which leads Dr. Burke to declare a "Code Black" for the hospital. Bailey worries where her husband is as she is in labor. Also Izzie and Alex may be creating some heat.

star 8.41
805 votes
Directors: Peter Horton
Writers: Shonda Rhimes
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Sanctuary

#7 - Sanctuary

Season 6 - Episode 23

Seattle Grace Hospital is hit with a crisis like no other in its' history.

star 8.40
770 votes
Directors: Stephen Cragg
Writers: Shonda Rhimes
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Fear (Of the Unknown)

#8 - Fear (Of the Unknown)

Season 10 - Episode 24

The doctors of Grey Sloan Memorial Hospital bid an emotional farewell to the beloved Cristina Yang. A possible act of terrorism rocks Seattle and causes chaos at the hospital. Meanwhile, Meredith makes a life changing decision and one doctor receives shocking news.

star 8.30
1,145 votes
Directors: Tony Phelan
Writers: Shonda Rhimes
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Freedom (2)

#9 - Freedom (2)

Season 4 - Episode 17

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

star 8.28
502 votes
Directors: Rob Corn
Writers: Shonda Rhimes
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What a Difference a Day Makes

#10 - What a Difference a Day Makes

Season 5 - Episode 22

As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation ceremony, is admitted to the ER. Meanwhile, Izzie fears the worst when she begins experiencing familiar symptoms.

star 8.27
672 votes
Directors: Rob Corn
Writers: Shonda Rhimes
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Get Up, Stand Up

#11 - Get Up, Stand Up

Season 10 - Episode 12

On the day of April's wedding, the Grey Sloan Memorial doctors are all preoccupied with their own drama. Meredith and Cristina continue to argue about their research and careers, Bailey comes clean to Ben about her feelings regarding him moving back to Seattle, and Shane puts himself in a risky situation. Meanwhile, Derek gets a phone call that will change his life.

star 8.25
1,167 votes
Directors: Tony Phelan
Writers: William Harper
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Suddenly

#12 - Suddenly

Season 8 - Episode 10

A severe car crash involving an entire family results in an all-hands-on situation in the ER, as the eldest daughter is left to make the toughest decision of her life. Meanwhile Teddy, still in the dark about Henry's death, calls upon Cristina to help with her patient in the O.R., and Lexie finds herself working alongside Mark's new girlfriend, Julia, during an eye surgery.

star 8.24
750 votes
Directors: Ron Underwood
Writers: Stacy McKee
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17 Seconds

#13 - 17 Seconds

Season 2 - Episode 25

George and Derek work together, Denny still doesn't have a heart, and Meredith gets paired with Callie. A 12-week pregnant girl dies in the O.R. and her parents try to keep the baby alive. This causes tension between Derek and Addison. One doctor's overreaction unites two bickering patients. Finn is still treating Doc for medical problems.

star 8.22
709 votes
Directors: Dan Minahan
Writers: Mark Wilding
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Deterioration of the Fight or Flight Response (1)

#14 - Deterioration of the Fight or Flight Response (1)

Season 2 - Episode 26

Denny needs a heart or else. Izzie and George go crazy trying to get him one. Derek has the life of a friend in his hands as he operates on Burke who has been shot. Burke cannot operate on Denny after Denny's heart stopped and now Denny is in a dire condition. Cristina gets put in charge of the ER and she is worried about Burke.

star 8.22
668 votes
Directors: Rob Corn
Writers: Joan Rater, Tony Phelan
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Drowning on Dry Land

#15 - Drowning on Dry Land

Season 3 - Episode 16

Almost everyone searches for Meredith while they ponder her place in the world. Addison considers pursuing Alex. Izzie takes desperate measures to manage the situation she is in. Someone ends up on the brink of death. Cristina and Burke have a blow-up fight about their announcement.

star 8.19
687 votes
Directors: Rob Corn
Writers: Shonda Rhimes
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Didn't We Almost Have It All?

#16 - Didn't We Almost Have It All?

Season 3 - Episode 25

Callie and George make a big decision. A successor to Chief Webber is named. A man named Jeff Pope arrives. He is looking for his wife and newborn child. Cristina and Burke's wedding day has arrived and so have the interns first-year exam results.

star 8.17
648 votes
Directors: Rob Corn
Writers: Tony Phelan, Joan Rater
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Into You Like a Train

#17 - Into You Like a Train

Season 2 - Episode 6

Train Wreck victims come to Seattle Grace and all staff gets called in. Everyone deals with really weird cases. Except Addison and Izzie. They work with a woman who is pregnant.

star 8.11
778 votes
Directors: Jeff Melman
Writers: Krista Vernoff
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Flight

#18 - Flight

Season 8 - Episode 24

Faced with a life threatening situation, the doctors must fight to stay alive while trying to save the lives of their peers; Bailey and Ben make a decision regarding their relationship; and Teddy is presented with a tempting offer. Meanwhile, Richard plans a special dinner for the residents.

star 8.11
838 votes
Directors: Rob Corn
Writers: Shonda Rhimes
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Who's Zoomin' Who?

#19 - Who's Zoomin' Who?

Season 1 - Episode 9

A sexually transmitted disease breaks out and affects several members of the hospital staff. Chief Webber promptly calls a meeting. Meanwhile, the chief reluctantly tells Dr. Derek Shepherd about his own medical concerns. Izzie and Cristina worry about a patient's wife and daughter who can't agree on his care. Burke treats his college buddy Bill, whose medical diagnosis raises some questions regarding his wife's actions. Then just as Meredith and Derek grow more intimate, a surprise is revealed.

star 8.10
789 votes
Writers: Gabrielle Stanton, Harry Werksman
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Walk On Water

#20 - Walk On Water

Season 3 - Episode 15

The staff is trying to deal with antsy patients while dealing with a major disaster when a cargo ship strikes a Ferryboat in Seattle. The Chief must choose a team to go out on location and save what is left of the few lives spared.

star 8.09
689 votes
Directors: Rob Corn
Writers: Shonda Rhimes
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Family Affair

#21 - Family Affair

Season 12 - Episode 24

Meredith and Maggie support Amelia on an important day; Jo reveals that she has been keeping secrets from Alex while Arizona and Callie deal with the impact of their custody arrangement. Meanwhile, Ben leaps into action to help a friend.

star 8.08
2,236 votes
Directors: Debbie Allen
Writers: William Harper
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Dark Was the Night

#22 - Dark Was the Night

Season 8 - Episode 9

Teddy puts her husband’s life in the hands of her peers when Henry is sent to the OR for surgery and she’s called away on another case; Meredith and Derek receive the long-awaited news about Zola; Callie and Jackson come under fire when their patient experiences post-surgery complications; and Meredith and Alex are involved in a life-threatening situation when they travel to a neighboring hospital to tend to a sick newborn, on Grey’s Anatomy

star 8.08
746 votes
Writers: Debora Cahn
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Some Kind of Miracle

#23 - Some Kind of Miracle

Season 3 - Episode 17

Everyone is pushing for Meredith to survive, or in this case to be revived. People are still dealing with the fallout from the ferry disaster. A young man named Lucas is having problems with brain-mouth coordination. Someone else dies.

star 8.08
666 votes
Directors: Adam Arkin
Writers: Shonda Rhimes, Marti Noxon
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This is Why We Fight

#24 - This is Why We Fight

Season 9 - Episode 16

As word of Seattle Grace's financial trouble spreads, Catherine encourages Jackson to move to Boston, and the interns fear they might lose their jobs. Meanwhile, the doctors meet with a potential investor in a last-ditch effort to save the hospital, and Alex impresses Jo while caring for a patient.

star 8.08
785 votes
Directors: Jeanott Szwarc
Writers: Austin Guzman
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Freedom (1)

#25 - Freedom (1)

Season 4 - Episode 16

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

star 8.08
594 votes
Directors: Rob Corn
Writers: Shonda Rhimes
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