The BEST Episodes of Grey's Anatomy

Every episode ever - ranked by fan votes!

Last Updated: Oct 18, 2021

Network: ABC (US)

A drama centered on the personal and professional lives of five surgical interns and their supervisors.

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Death and All His Friends

#1 - Death and All His Friends

Season 6 - Episode 24 - Aired May 20, 2010

Cristina and Meredith's surgical skills are put to the ultimate test.

star 8.31
3,445 votes
Directors: Rob Corn
Writers: Shonda Rhimes
Losing My Religion

#2 - Losing My Religion

Season 2 - Episode 27 - Aired May 15, 2006

This episode is the second part of a two-hour season finale. Richard tries to get information from Addison about a family member's condition. Callie and George have a talk about his feelings. Meredith and Derek have a talk about Doc.

star 8.23
1,315 votes
Directors: Mark Tinker
Writers: Shonda Rhimes

#3 - Sanctuary

Season 6 - Episode 23 - Aired May 20, 2010

Seattle Grace Hospital is hit with a crisis like no other in its' history.

star 8.20
3,261 votes
Directors: Stephen Cragg
Writers: Shonda Rhimes
Silent All These Years

#4 - Silent All These Years

Season 15 - Episode 19 - Aired Mar 28, 2019

When a trauma patient arrives at Grey Sloan, it forces Jo to confront her past. Meanwhile, Bailey and Ben have to talk to Tuck about dating.

star 8.16
1,194 votes
Directors: Debbie Allen
Writers: Elisabeth Finch
Now or Never

#5 - Now or Never

Season 5 - Episode 24 - Aired May 14, 2009

In the second part of the two hour season finale, George delivers stunning news to Bailey, sending shockwaves throughout the hospital, and Izzie's friends anxiously await her recovery from surgery. Meanwhile Bailey is surprisingly displeased after being accepted into the pediatric fellowship program, and the victim of a near-fatal traffic accident brings the talents of Seattle Grace's doctors together. This is the second hour of a 2-hour season finale.

star 8.11
1,625 votes
Directors: Rob Corn
Writers: Debora Cahn
Cold as Ice

#6 - Cold as Ice

Season 14 - Episode 23 - Aired May 10, 2018

One of Grey Sloan Memorial’s own is seriously injured, making the team reflect on what is truly important to them. Meanwhile, Nicole Herman pays a visit to GSM and talks to Arizona about an exciting opportunity.

star 8.10
1,543 votes
Directors: Bill D'Elia
Writers: Bill Harper
It's the End of the World

#7 - It's the End of the World

Season 2 - Episode 16 - Aired Feb 5, 2006

An explosive case arrives at the O.R. that might endanger all the lives of the people working there, which leads Dr. Burke to declare a "Code Black" for the hospital. Bailey worries where her husband is as she is in labor. Also Izzie and Alex may be creating some heat.

star 8.09
1,625 votes
Directors: Peter Horton
Writers: Shonda Rhimes
All of Me

#8 - All of Me

Season 14 - Episode 24 - Aired May 17, 2018

The doctors attend Alex and Jo’s wedding, and things do not go as planned. Meanwhile, the stress from the past year has taken a toll on Bailey, and she will re-evaluate some of her decisions.

star 8.05
1,493 votes
Directors: Debbie Allen
Writers: Krista Vernoff
Ring of Fire

#9 - Ring of Fire

Season 13 - Episode 24 - Aired May 18, 2017

In the season finale, the doctors' lives are at risk after a dangerous patient escapes the hospital room. Alex must make a hard choice in his relationship with Jo while Meredith has some big news for Nathan that brings things to a turning point.

star 8.05
3,436 votes
Directors: Debbie Allen
Writers: Stacy McKee
Family Affair

#10 - Family Affair

Season 12 - Episode 24 - Aired May 19, 2016

Meredith and Maggie support Amelia on an important day; Jo reveals that she has been keeping secrets from Alex while Arizona and Callie deal with the impact of their custody arrangement. Meanwhile, Ben leaps into action to help a friend.

star 8.04
2,506 votes
Directors: Debbie Allen
Writers: William Harper
Freedom (2)

#11 - Freedom (2)

Season 4 - Episode 17 - Aired May 22, 2008

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

star 8.04
1,221 votes
Directors: Rob Corn
Writers: Shonda Rhimes
Fear (of the Unknown)

#12 - Fear (of the Unknown)

Season 10 - Episode 24 - Aired May 15, 2014

The doctors of Grey Sloan Memorial Hospital bid an emotional farewell to the beloved Cristina Yang. A possible act of terrorism rocks Seattle and causes chaos at the hospital. Meanwhile, Meredith makes a life changing decision and one doctor receives shocking news.

star 8.04
1,920 votes
Directors: Tony Phelan
Writers: Shonda Rhimes
As We Know It

#13 - As We Know It

Season 2 - Episode 17 - Aired Feb 12, 2006

Derek is still operating when he finds out about Meredith's current situation. Meredith is freaking out about her situation. Webber and Bailey are dealing with medical health issues. Cristina and Izzie have their own issues to deal with because of Meredith's situation. Addison freaks out when George tries to find a solution to Bailey's impromtu postponement. Overall, Seattle Grace Hospital is still under code black and the situation is getting worse.

star 8.04
1,466 votes
Directors: Peter Horton
Writers: Shonda Rhimes
My Shot

#14 - My Shot

Season 16 - Episode 8 - Aired Nov 14, 2019

Meredith faces the medical board as her future as a doctor remains uncertain, and she’s forced to reckon with her past in some challenging ways. Meanwhile, the interns are put to the test as they are each vying to be the most successful on their respective cases in the absence of some of the attendings.

star 8.01
841 votes
Directors: Debbie Allen
Writers: Meg Marinis
Perfect Storm

#15 - Perfect Storm

Season 9 - Episode 24 - Aired May 16, 2013

Grey Sloan Memorial Hospital enters crisis mode as the storm rages, resources become scarce and patients flood in by the busload. Meanwhile, one of the doctors fights for their life.

star 7.98
2,379 votes
Directors: Rob Corn
Writers: Stacy McKee
Get Up, Stand Up

#16 - Get Up, Stand Up

Season 10 - Episode 12 - Aired Dec 12, 2013

On the day of April's wedding, the Grey Sloan Memorial doctors are all preoccupied with their own drama. Meredith and Cristina continue to argue about their research and careers, Bailey comes clean to Ben about her feelings regarding him moving back to Seattle, and Shane puts himself in a risky situation. Meanwhile, Derek gets a phone call that will change his life.

star 7.98
2,171 votes
Directors: Tony Phelan
Writers: William Harper
Didn't We Almost Have It All?

#17 - Didn't We Almost Have It All?

Season 3 - Episode 25 - Aired May 17, 2007

Callie and George make a big decision. A successor to Chief Webber is named. A man named Jeff Pope arrives. He is looking for his wife and newborn child. Cristina and Burke's wedding day has arrived and so have the interns first-year exam results.

star 7.98
1,259 votes
Directors: Rob Corn
Writers: Joan Rater, Tony Phelan
True Colors

#18 - True Colors

Season 13 - Episode 23 - Aired May 11, 2017

The doctors of Grey Sloan encounter a difficult case involving a dangerous patient. Meanwhile, Owen receives life-changing news that pushes Amelia to step up to support him, and Alex attends a medical conference after making a shocking discovery.

star 7.98
3,504 votes
Directors: Kevin McKidd
Writers: William Harper

#19 - 1-800-799-7233

Season 14 - Episode 9 - Aired Jan 18, 2018

Jo finally faces her estranged, abusive husband Paul Stadler, while Grey Sloan continues to work with the FBI after a hacker has compromised the hospital’s computer system.

star 7.96
2,186 votes
Directors: Bill D'Elia
Writers: Andy Reaser
Out of Nowhere

#20 - Out of Nowhere

Season 14 - Episode 8 - Aired Nov 16, 2017

A hacker compromises the hospital’s computer system, causing monitors, phones, labs and patient files to all go down. As technology fails them, Bailey attempts to keep the peace but chaos erupts and the doctors are forced to get creative in their methods to treat the patients.

star 7.95
2,481 votes
Directors: Kevin McKidd
Writers: William Harper
Who Lives, Who Dies, Who Tells Your Story

#21 - Who Lives, Who Dies, Who Tells Your Story

Season 14 - Episode 7 - Aired Nov 9, 2017

After a roller coaster car falls off the track at the county fair, the doctors at Grey Sloan tend to patients who spark memories about ghosts from their past. The series 300th episode!

star 7.94
2,419 votes
Directors: Debbie Allen
Writers: Krista Vernoff
Drawn to the Blood

#22 - Drawn to the Blood

Season 15 - Episode 24 - Aired May 9, 2019

Alex tries desperately to save his patient Gus while he waits for a severely agoraphobic blood donor to arrive from London. Jo reveals to Meredith why she’s been so down, while Catherine and Bailey hold a meeting to get down to the bottom of an insurance issue. Meanwhile, Maggie and Jackson go camping.

star 7.92
1,026 votes
Directors: Kevin McKidd
Writers: Andy Reaser
17 Seconds

#23 - 17 Seconds

Season 2 - Episode 25 - Aired May 14, 2006

George and Derek work together, Denny still doesn't have a heart, and Meredith gets paired with Callie. A 12-week pregnant girl dies in the O.R. and her parents try to keep the baby alive. This causes tension between Derek and Addison. One doctor's overreaction unites two bickering patients. Finn is still treating Doc for medical problems.

star 7.92
1,476 votes
Directors: Dan Minahan
Writers: Mark Wilding
Blowin' in the Wind

#24 - Blowin' in the Wind

Season 15 - Episode 8 - Aired Nov 15, 2018

Seattle is hit by a huge windstorm and Grey Sloan becomes inundated with patients; Alex and Jo are stuck at home and decide to make the best of it by having a second honeymoon; Meredith confronts Richard about getting his life back on track

star 7.91
1,245 votes
Directors: Kevin McKidd
Writers: Meg Marinis
Put on a Happy Face

#25 - Put on a Happy Face

Season 16 - Episode 21 - Aired Apr 9, 2020

Link tries to convince Amelia to take it easy during the final stage of her pregnancy. Hayes asks Meredith a surprising question, and Owen makes a shocking discovery.

star 7.91
706 votes
Directors: Deborah Pratt
Writers: Mark Driscoll, Tameson Duffy