A late 20th-century New York City pizza delivery boy, Philip J. Fry, after being unwittingly cryogenically frozen for one thousand years, finds employment at Planet Express, an interplanetary delivery company in the 31st century.
After a string of bad luck, Fry ventures into the decaying ruins of Old New York to regain his lucky seven-leaf clover from his childhood, only to find that his brother Yancy Fry had stolen not only the clover, but Fry's identity as well. Fry sets out to exhume his brother's body, but discovers the startling truth about Yancy instead.
Fry discovers his dog Seymour is being exhibited in a museum as a fossil, and takes it to Professor Farnsworth's lab to be revived. However, Bender is displeased with the lack of attention he has been receiving and becomes increasingly jealous of Seymour's fossil.
Fry, a 20th-century New-York pizza delivery boy receives a prank call and is frozen in a capsule and wakes up in year 2999. He meets an alien named Leela that wants to assign his permanent career... delivery boy. Fry refuses, so he escapes. He then meets Bender, a robot who likes to drink and has suicidal tendencies. Together, they start running away from Leela, arriving to the ruins of old New York. Leela finds them, but instead of inserting the permanent chip on Fry, she removes her own. All three go to Prof. Hubert Farnsworth's house, Fry's only living relative, becoming his new space crew.Watch Now:AmazoniTunes
Desperate to learn how to play the holophonor in order to impress Leela, Fry swaps hands with the Robot Devil. He goes on to become a skilled holophonor player, winning Leela's heart and penning an opera about her life story, but the Robot Devil still has a trick or two up his sleeve.
Fry leads the crew on a quest across the galaxy to regain the forbidden 79 episodes of "Star Trek: The Original Series", where they encounter the original cast of the show - as well as their captor, an obsessive energy being named Melllvar.
A mission to collect honey from deadly space bees apparently leads to Fry's sting-induced death. Leela is wracked with remorse, until Fry visits her in her dreams. As Leela's hallucinations intensify, she begins to suspect that she might be going crazy.
When Fry becomes infested with parasitic worms that make him stronger and smarter, he finally finds the perfect way to profess his feelings to Leela. Meanwhile, the rest of the crew goes on a journey into Fry's body to eradicate the worms.Watch Now:AmazoniTunes
While creating a team of mutants to play the Harlem Globetrotters, the Professor accidentally causes a disruption in time that threatens the existence of the universe. Meanwhile, Fry tries to win an unreceptive Leela's heart.
Still unable to impress Leela, Fry sadly suspects that he has no importance in life - until Nibbler takes him on a mission to prevent the brains from destroying the universe. In the process, Fry learns what really happened when he was cryogenically frozen on December 31, 1999.
A flower stand owner falls in love with Doctor Zoidberg, unable to smell his unpleasant odor due to being born without a sense of smell. Their budding romance is challenged when Zoidberg has the opportunity to give her a nose transplant and restore her sense of smell.
A double-date for Kif, Amy, Zapp, and Leela ends in disaster when their orbiting restaurant crashes on planet Amazonia. The hulking female inhabitants of the planet take their male captives to the omniscient Femputer, who orders Fry, Zapp, and Kif to death by "snu-snu".
Bender is accidentally shot out of the ship's torpedo tube and becomes lost in space. Floating through the ethereal darkness, Bender becomes inhabited with tiny alien life forms, but has trouble playing God to their unyielding prayers.
The crew's attempts to de-age Professor Farnsworth result in everyone returning to their more youthful stages. While Farnsworth seeks out a way to re-age the crew, the newly-teenaged Leela takes the opportunity to experience the parental childhood she never had.
The Professor's "What-If" machine simulates Bender, Leela and Fry's wishes. Bender discovers what it would be like if he were 500 feet tall, Leela discovers what it would be like if she were more impulsive, and Fry discovers what would happen if he never came to the future.Watch Now:AmazoniTunes
When Bender disposes nuclear waste in the sewers, the angry mutants drag him, Fry, and Leela down to the depths to be mutated. As they attempt to escape, Leela makes an incredible discovery about her true heritage, finally meeting her parents for the first time.
Earth is invaded by super-intelligent flying brains, who sap the Earth's populace of their intelligence. Leela is taken to Nibbler's home planet Eternia, where the Nibblonians explain that only one human is immune to the brains' powers - Fry.