The BEST episodes of Holby City season 21

Every episode of Holby City season 21, ranked from best to worst by thousands of votes from fans of the show. The best episodes of Holby City season 21!

This series is a spin-off from the long running BBC medical drama Casualty. Set in the same hospital as its sister series, this show follows the everyday lives, professional and personal, of the doctors, nurses and patients who find themselves, for various reasons, in the wards of Holby City General Hospital.

Last Updated: 3/21/2024Network: BBC OneStatus: Ended
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Divine Justice
star
8.36
11 votes

#1 - Divine Justice

Season 21 - Episode 40 - Aired 10/1/2019

Will it be Chloe or Evan’s version of events that will be believed? How can a grieving Cameron make amends for failing Chloe when she needed him most? And what will an MRI scan reveal about Ric’s future?

Circle of Life
star
8.15
13 votes

#2 - Circle of Life

Season 21 - Episode 38 - Aired 9/17/2019

Ric fears for his health, leading him to withdraw just as his granddaughter goes into premature labour. Cameron steps in to take charge, and forces Ric to face up to his fears. Essie's false claim to be Isla's adoptive mother stands to be exposed when the girl requires emergency surgery, and Chloe throws herself back into work in the hope of moving on from Evan - but is gripped by a paranoid belief that someone is spying on her.

Lemons
star
8.08
12 votes

#3 - Lemons

Season 21 - Episode 51 - Aired 12/17/2019

Lofty and Dom prepare to renew their wedding vows with some special guests - but Lofty has begun to question the validity of their marriage, and is forced to consider what he really wants out of life. Sacha's daughter gives some tough advice, and Chloe tries to decide what she wants to do about her pregnancy, and realises she must tell Ange everything if she is to find peace.

Powerless
star
8.06
18 votes

#4 - Powerless

Season 21 - Episode 10 - Aired 3/5/2019

After a computer virus shuts down the hospital's power, Jac and Connie fight to save the lives of close friends. As the hospital is evacuated, Ric mounts a desperate rescue for a trapped Essie. Meanwhile, Ange and Serena clash over Holly's care and continued life support.

Directors: Steve Brett
The Perfect Storm
star
8.00
12 votes

#5 - The Perfect Storm

Season 21 - Episode 36 - Aired 9/3/2019

As the town is engulfed by a storm, Jac faces a devastating confrontation with her old rival Faye Byrne and the man whom they both loved. Sacha helps a grieving family that is torn over the issue of organ donation to come to a difficult decision. Patsy Kensit reprises her role as Faye for the first time since 2010.

Blurring the Lines
star
8.00
5 votes

#6 - Blurring the Lines

Season 21 - Episode 48 - Aired 11/26/2019

Kian is desperate to deliver the surgery that Bea desires, but Jac is too stressed and refuses to help, forcing him to consider what he is willing to sacrifice to give her what she wants. Dom and Lofty are too busy putting others first to deal with their own problems, and Donna distracts herself from her troubles by focussing on a returning patient. But when she goes missing, Donna has to be brave enough to convince them both to face their fears.

Bell Jar
star
8.00
15 votes

#7 - Bell Jar

Season 21 - Episode 49 - Aired 12/3/2019

Elliot is in urgent need of life-changing surgery, and Jac is the only person qualified to perform it - but her struggles with anxiety may put his life on the line. Cameron gets a chance to make amends for his past mistakes, but goes about it the wrong way by manipulating a patient's relative. Carole returns from holiday blissfully unaware of what Dom and Lofty are going through.

Retreat
star
7.90
10 votes

#8 - Retreat

Season 21 - Episode 39 - Aired 9/24/2019

Evan refuses to give up on Chloe, and Cameron receives heartbreaking news

This Be the Verse
star
7.90
10 votes

#9 - This Be the Verse

Season 21 - Episode 41 - Aired 10/8/2019

Both Ric and Darla are faced with life-changing decisions, an aggressive stranger at the hospital threatens to blow Essie’s baby secret wide open, and will Kian be able to mend the heart of an old flame?

Ask No Questions
star
7.88
16 votes

#10 - Ask No Questions

Season 21 - Episode 14 - Aired 4/2/2019

Chloe is wrong-footed when ex-boyfriend Evan unexpectedly turns up on Darwin. As Ange reels from her recent discovery, Dom is also confronted with life-changing revelations. And when Mia appears on the ward, Donna faces some tricky parenting dilemmas.

Babysitters and Bystanders
star
7.85
13 votes

#11 - Babysitters and Bystanders

Season 21 - Episode 35 - Aired 8/27/2019

Phoebe is admitted to hospital, and Evan accompanies her. Chloe is left dismayed by the development, as there seems to be no hope of cutting him out of her life altogether. Essie must make a difficult decision when a former patient asks her for a drastic favour, and Ric is concerned when a member of the Trust is admitted, and places the patient in Cameron's hands.

Honeymoon
star
7.83
12 votes

#12 - Honeymoon

Season 21 - Episode 29 - Aired 7/16/2019

As her loved ones continue to worry about her, Chloe learns more about Evan. Cameron wants to get out from under Bernie’s shadow, but he receives some devastating news. Hanssen learns that his grandson is not the only one who believes in the tooth fairy.

The Wrong Horse
star
7.79
14 votes

#13 - The Wrong Horse

Season 21 - Episode 20 - Aired 5/14/2019

Struggling with the news that Dominic is her half-brother, Chloe is forced to operate with him. Lofty returns to Holby with a secret.

Be True, Be Brave, Be Kind
star
7.79
14 votes

#14 - Be True, Be Brave, Be Kind

Season 21 - Episode 52 - Aired 12/19/2019

Bea requires emergency surgery, so Kian takes matters into his own hands, despite having been suspended - will this be the end of his career? Essie has a run-in with new consultant Ben Sherwood, just as Sacha encourages her to give him a second chance - although he may soon regret it. Dominic throws himself into work after receiving his divorce papers for Christmas.

Hope Is a Powerful Drug
star
7.77
13 votes

#15 - Hope Is a Powerful Drug

Season 21 - Episode 42 - Aired 10/15/2019

Frankie returns to Holby, keen to take Isla back. Essie is not convinced she is truly ready for the demands of parenthood, and tries to persuade her to leave her daughter behind. A top neurosurgeon has a radical idea for how to treat Ric's tumour, but Serena is not convinced by the plan. Ric is left to consider both their positions, and decide what he wants to do. Jac returns from holiday, and asserts her authority over an overworked Kian.

Remember, Remember
star
7.75
12 votes

#16 - Remember, Remember

Season 21 - Episode 45 - Aired 11/5/2019

In Holby City's 1,000th episode, a familiar face returns for the hospital's 150th anniversary. Ric is discharged, but is this the last Holby will see of him?

Reckless
star
7.71
14 votes

#17 - Reckless

Season 21 - Episode 28 - Aired 7/10/2019

Chloe's day is thrown into chaos when Evan is attacked, and with his life on the line, he asks her a surprising question. Dominic is put under pressure when a surprise visitor arrives at Holby looking for Lofty. Wanting to keep his marriage intact, Dominic is forced to make a difficult decision. After a night of partying together, Serena and Fleur Fanshawe are thrown together to help a patient on AAU.

Kintsugi
star
7.71
14 votes

#18 - Kintsugi

Season 21 - Episode 50 - Aired 12/10/2019

Jac is confined to a psychiatric unit, and refuses to accept that she has a problem. However, a visit from Fletch, Sacha and Elliot convinces her that things have to change for Emma's sake. Chloe receives some life-changing news, and decides that she has to tell Evan's sister the truth about her dead brother. Zav and Cameron try to save the life of a girl who has been stabbed, only to discover a disturbing truth behind the attack.

Gods and Monsters
star
7.63
16 votes

#19 - Gods and Monsters

Season 21 - Episode 37 - Aired 9/10/2019

Ric celebrates his 65th birthday, but as he continues to make mistakes at work, the return of a face from the past forces him to realise that his surgical skills are fading. Fletch risks his chances of making peace with Ange as he tries to discover if Chloe's story is true, and Essie is forced to assume the role of a newly adoptive mother after Sacha jumps to the wrong conclusion.

Never Say Never
star
7.62
13 votes

#20 - Never Say Never

Season 21 - Episode 8 - Aired 2/19/2019

Zosia returns to Holby looking for work, while a frustrated Jac tries to track down Frieda. Elsewhere, Ange admits there is no hope for her patient, Holly, while Donna and Xavier clash over their new living arrangements.

Kiss Kiss
star
7.59
17 votes

#21 - Kiss Kiss

Season 21 - Episode 26 - Aired 6/25/2019

Xavier tries to build bridges with Donna, but she’s having none of it. Cameron can’t quite shift his feelings of unease around Evan, and when he overhears a phone call his suspicions are confirmed. And Fletch is anxious about his first official date with Ange, especially when work threatens to get in the way.

Directors: Paulette Randall
The Burden of Proof
star
7.58
12 votes

#22 - The Burden of Proof

Season 21 - Episode 3 - Aired 1/15/2019

Dominic desperately tries to inveigle his way into working alongside new Consultant, Ange Goddard, only to find that she's not that impressed with him. Meanwhile, Cameron bites off more than he can chew when he clashes with Jac, and Ric's ex-wife returns as a locum for the day, much to his dismay.

Work-Life Balance
star
7.57
14 votes

#23 - Work-Life Balance

Season 21 - Episode 33 - Aired 8/13/2019

Is Chloe brave enough to tell Evan she wants a divorce? And what will he do if she does? Faced with choosing between work and his personal life, will Hanssen learn from past mistakes? And will having their therapist as a patient bring Dom and Lofty closer or push them further apart?

Directors: Julie Edwards
Writer: Simon Norman
Sandra's Choice
star
7.57
7 votes

#24 - Sandra's Choice

Season 21 - Episode 46 - Aired 11/12/2019

As Elliot's concern for Jac grows, will he ever be able to tell her his secret? Lofty is determined to be there for his new family, but will it be smooth sailing from here? Sacha is conflicted when his feelings for Essie resurface.

Directors: Thomas Hescott
Mothers and Their Daughters
star
7.50
8 votes

#25 - Mothers and Their Daughters

Season 21 - Episode 53 - Aired 12/31/2019

Confronted with an unwelcome patient, Serena is forced to make a life or death choice. Chloe decides she's ready to move on in 2020, but will her decision hurt a good friend? And Ange and Fletch plan their first New Year's Eve together, but will Sacha and Dominic's interference scupper their plans?