ER follows the medical personnel and patients in the emergency room of Chicago's fictional County General Hospital. The doctors and nurses of County's ER confront the daily challenges of a busy urban hospital, including overcrowded waiting rooms, staffing shortages, and the impact of life-and-death decisions. While they teach the next generation of doctors, each must tackle the demands of their personal lives, at times unsuccessfully.
A belligerent young man with the flu presents a challenge to Morris and Sam when he refuses treatment, and later turns out to be more than he seems to be. Luka and Abby’s childcare emergency means balancing baby care with patient care in the ER until a nanny can be found, but the candidates prove less than satisfactory. Luka has an uneasy encounter with Curtis Ames at the hospital, and later Abby and Baby Joe have a "chance" encounter with Ames at the park. Pratt discovers a local church's risky drug exchange program. Neela and Gates square off at an M&M.
Carter works in the Sudanese desert, helping treat hundreds of diseased people including a woman raped by a militant group. Back in the ER, the police accuse Clemente of shooting Jodie. Pratt and Neela work to save a 14-year-old involved in a hit-and-run accident, but Pratt is infuriated when he discovers who hit the young teen. Kovač refuses to let Clemente return to work until he is reviewed by the Impaired Physician Committee. Jodie awakens from her coma and tells the police about her shooting, and Bobby threatens Clemente's life.
After hearing that Kem's mother is sick, Carter flies to Paris to see Kem. While there, Carter offers to move back to Africa to start all over. Birdie and Rebecca are back; Rebecca was strangled by their niece Shelley, so Birdie stabbed Shelley. Neela, Abby and Ray all make rookie mistakes with various patients. While in counseling, Sam reveals that she thinks that she and Kovač should not be together. Abby makes it clear that she and Jake do not have a future together.
Alex is set to be released from the hospital. Doctors treat African-American brothers Curtis Bennet, 17, who has abdominal pain and 10-year-old Quincy Bennet who has a knee injury. Both were injured during a drug deal that went terribly wrong. There's still some residual tension between Gates and Sam. A female patient in police custody doesn't want to be examed by Morris. A 13-year-old patient named Anastasia messes with Neela's love life.Watch Now:iTunes
Banfield and Morris go to the coffee shop at 3 a.m. and are served by 20-year-old Debbie who is six-months pregnant. The doctors treat someone with a heart problem and Alex. Chaz must look for a missing 7-year-old boy who saw his sister die.Watch Now:iTunes
Doctors take care of 24-year-old Gloria Ortiz who is 8 months pregnant. The woman fell during an immigration raid at a tie factory and started getting contractions. Coburn discovers that the baby has a mass in the neck and head area… maybe cancer? Immigration agents come to the hospital to take Gloria into custody. Banfield has Morris do paperwork instead of seeing patients. Frank plans to dress up as Santa for the Christmas party. Neela has no intentions on going to said party claiming that last year turned out bad since Morris pinched her butt and Frank almost threw up on her. Sam pushes Dubenko to extubate Alex today instead of tomorrow. Neela is at the center of a malpractice suit.Watch Now:iTunes
Pratt is left in charge of a busy night shift, with only a few med students and fellow 2nd year Dr. Coop. Pratt makes a mistake with one of his patients. Abby is looking for a loan, she finally gives in and begs her ex-husband to co-sign. Romano gets his Utah arm. Abby visits Luka, finding Gillian in the middle of saying goodbye. Corday and Dorset are sleeping together, although Corday wonders if it's too soon after Mark's death.
In the wake of heavy rains, the ER is flooded with diverse patients, including a baby involved in a suspicious car crash with her mother and a heart-attack victim visited by his sex therapist. Sam confronts Eve about her strict ways. Abby learns the details of Dubenko's condition and tactfully refuses his advances. Kovač protests when nursing home workers drop off Blaire Collins, who has been comatose for six years, for routine care, but later in the day, she unexpectedly regains consciousness.Watch Now:iTunes
Lewis, Neela, and Sam are legally blocked from treating a woman dying from the effects of a hunger strike designed to prevent her son from being deported. Pratt struggles to find a way to convince a woman with breast cancer to seek treatment. Abby treats two elderly sisters involved in a mugging. To Weaver's delight, Carter donates $150 million to the hospital's new venture, in exchange for naming rights. Carter calls Kem and asks her opinion on The Joshua Carter Center, named after their stillborn son.
Gallant and Neela have been exchanging letters regularly. Gallant struggles with the war he sees every day, while Neela is searching for her life's purpose. Gallant enlists Neela's help in getting a critically burned Iraqi girl lined up for surgery in Chicago and heads for the U.S. with 72 hours leave.
Neela has a recurring dream; Gates tries to save a patient who jumped out of a window while sleeping; Neela is surprised to see Dr. Corday.Watch Now:iTunes
Everyone in the ER is trying to cope with the loss of their colleague. The staff feels defensive toward the new Chief and her tough disposition. Gates and the new interns treat a bio terrorist, who has a lethal secret that endangers them all. Neela makes a great effort to get Dubenko back on the surgery staff, and gets help from an unexpected souce.
Weaver prepares to call her birth mother, while she treats a man who was accidentally run over by his daughter while she was drunk. Susan's first day back is typically hectic, as she treats a girl with an ectopic pregnancy who refuses to stay for treatment and a man faking a coma to escape his bookie. Abby seems to notice the chemistry between Susan and Carter and gets a little jealous. Cleo has gotten a better job 40 minutes outside of Chicago. The Greene household is pretty crazy now that Rachel is living there. After Elizabeth loses another patient to a post-op infection, an investigation is launched and someone is assigned to shadow her all day to check her cleanliness. Benton panics when Roger reveals that he can't find Reese--it turns out that Jackie picked him up from school after he got in a fight. Carter's day as chief resident is marred a little when his grandmother comes to the ER after slipping.
Third year med student (and part-time OB nurse) Abby Lockhart begins her ER rotation. A flu bug sweeps through the ER. Carter tries to help a kid with muscular dystrophy while Cleo treats a kid who's been injecting hormones into himself. Corday discovers that her mother will be coming to town and then decides to pay her a visit. Lucy treats a dying homeless man. Benton and Romano clash over the treatment of a surgical case. Luka and Carol treat a young boy whose mother is injecting him with saline to get surgical procedures done.
Dr. Banfield is irritated when Morris takes Chaz under his wing and teaches him risky medical procedures; Neela is unhappy when Dr. Banfield undermines her authority with an intern.Watch Now:iTunes
A frantic Sam and Luka report diabetic Alex missing after he runs away to find his father. Acting on information from the police, they follow a lead to Iowa, then eventually head for Colorado. As they travel, they discuss their relationship, Sam tells Luka she doesn't want anymore kids. After finding Alex safe, Sam tells him the truth and takes him to see his father. In the ER, Susan, Pratt, and the nurses evaluate Ray, Neela, and Abby’s first days as R2s, while each of them struggle to manage patients, new interns, and their first attempts at teaching.Watch Now:iTunes
Morris tries to help a girl who was hit while riding her bike; Gates can't get over his feelings for Sam; Neela is flustered when Dr. Brenner returns from Australia.Watch Now:iTunes
It is Neela's first day back at the ER and Pratt orders each intern to discharge 25 patients by the end of their shift, tracking their output. Neela struggles with frustration as she trails in the competition and is asked rude personal questions by a medical student Jane Figler while trying to help a patient with severe leukemia. Ray leads by a landslide, but makes a major mistake by green-lighting organ donation against the family's wishes after he sped through the paperwork. Not interested in the competition, Abby fakes a needle prick in order to get HIV-protective medication for a worried patient- and deals with a med student who is smitten for her. Dubenko looks out for Abby when Ray rides all over her in a trauma. Dubenko is also a little obsessed with physics.
Alderman Bright returns to blackmail Weaver into treating his gay lover for syphilis (off the records, of course). Unfortunately, the man dies from an allergic reaction to penicillin and Kerry is forced to cover up her mistake. Carter and Abby come to terms with their ailing romance. Luka has a very unconventional therapy session. Romano's condition forces Anspaugh to replace him as chief of staff… with Weaver.
Dr. Banfield takes a run to clear her head but finds herself trying to rescue a three-year-old girl from drowning in a nearby lake. Gates tries to pull some strings in the ER to help his homeless war hero. Banfield is reminded of her own experience at County with Dr. Greene caring for her son as she tries to save the young three-year-old girl from certain death. Meanwhile, the interns continue to struggle to keep up in the ER.Watch Now:iTunes
Sam gets frustrated with Gates when he gets obsessed with finding a homeless war hero. Neela is upset at her intern after he gets the entire surgery department into a lawsuit. A husband and wife come into the ER after someone tried to burn down their home. Brenner loses his cool with a patient and it gets physical.Watch Now:iTunes
Back from Iraq, Gallant surprises Neela by impulsively asking her to marry him. Kerry steps in to the Kovac/Clemente battle, encouraging them to get along, which results in a competition to be agreeable. Ray and a somewhat rusty Kerry treat a man with hypothermia, leading Morris to take a stand regarding the best course of action. Luka, Clemente and Sam treat a boy with HIV whose mother refuses to believe HIV causes AIDS. At the day’s end, Neela and Gallant are married, despite Neela’s doubts. At the reception, Luka and Abby celebrate his appointment as Chief of Emergency Medicine and realize they want more than just friendship.Watch Now:iTunes
Ray attends to a surrogate mother who goes into labor prematurely after being involved in a car accident. A difficult decision must be made as the baby's life hangs in the balance. Pratt gets a visit from his estranged father Charlie. A depressed Kovač copes with another failed relationship when Sam announces she's moving out, but he gets emotional support from Abby, who joins forces with Neela to put a spoiled, rude patient in her place.
Kovac is in Chicago looking for hospice-care work. Neela's aorta surgery has caused an infection in her patient. Abby treats a teen who has been beaten up. Brenner continues to cause problems for the ER staff.Watch Now:iTunes
Lewis, Neela, and Ray treat a police officer shot during a robbery. His 15-year-old son must make a difficult decision on his father's course of treatment and he turns to Ray for advice. Ray promises to help the boy explain his decision to his mother, but he instead leaves for a gig and later gets an angry earful from Neela after the boy is browbeaten into changing his mind. Abby and Dubenko help a young girl whose mother does not want her to have critical surgery at County, but her condition worsens before her transfer can go through. Luka begins to take a more active role in Alex's life after he's suspended for bringing a copy of Maxim to school. An exhausted Chen returns to work, where Pratt finds her stealing potassium.