Hannibal Heyes and Kid Curry, two successful and popular outlaw cousins in the old West, decide it's time to go straight. The problem is that the governor just can't give them amnesty right away, they have to prove that they deserve it. And in the meantime they will still be wanted. Hunting them is everybody, from sheriffs to bounty hunters, to posses and ordinary people. Hannibal Heyes/Joshua Smith is the thinker, the poker player and the optimist, while Kid Curry/Thaddeus Jones is the quick-drawing worrier who sometimes is a bit slow. Together they are Smith and Jones... Other regular characters include "Big Mac" McCreedy, a wealthy ranch owner, who's feuding with his next door neighbour, senor Armendariz. Harry Briscoe is an agent with Bannerman detective agency, who's perhaps not the brightest man around. Clementine Hale is a woman with an enormous zest for life. She owns the only picture of Heyes and the Kid and often uses it to get them to get her out of trouble.
Someone's trying to get the guys out of a town where they are helping a widow run from the saloon left to her by her late husband, but they can't figure out who's doing it or why.
A saloon entertainer and a special agent suspect that Heyes and Curry's interest in a condemned robber is the same as their own; a rumored fortune in stolen buried gold.
After nearly three years of staying out of trouble, for the sake of the amnesty, it's finally time. But when Heyes and the Kid meet sheriff Trevors, they find out that the governor has been removed from office. The new governor, however, seems nicer. He promises them amnesty, as soon as they do this one job for him. It seems that his daughter has fallen in love with an outlaw, and Heyes and the Kid must bring her back. The Kid takes it upon him to charm the daughter, and thus make it easier for them to take her with them. But the Kid hadn't counted on her boyfriend's jealous nature and fast gun...
After the Kid wins another duel (over a man who claimed the Kid was cheating), the boys are contacted and offered a job by a man called ""Doc"" Donovan. They are to come with him into Mexico, to rescue a hostage from Mexicans who only want their rightful money. The Kid senses that Doc knows who they are, but they cannot be certain, and why would he hire them instead of collecting the fee? They manage to sneak out the hostage, Mr Zulick, but are chased by the kidnappers. After a daring stunt, they lose their followers, and Mr Zulick can continue on his journey. Then, Doc turns them over to the sheriff... But where is Mr Zulick headed and why? And why does the sheriff want to let Heyes and the Kid go?
A travelling potion salesman and his daughter come into the boys' protection after they become the only witnesses to a lynching. But the company is soon found by the lynch mob, and they have to start to run if they're to survive. They try to find refuge at a nearby sheriff office, but when the opposing side make the witnesses a phony offer of buying their silence, it's up to Heyes and the Kid to talk them out of it. They will have to run again. But they can't run forever, and the mob catches up with them. It's time to take a stand. Can they withstand the attacks until Heyes comes back with reinforcements?
The boys accept the offer of a vacation - but doesn't realize that the activities during this vacation involves catching and taming wild horses. They and their friend, Bronc, check into a boarding house near where the horses are, and meet some people whose coach has broken down. Among them is Beegee, a woman on the look-out for a husband, and who takes a good look at both Heyes and the Kid. And then there's the very religious man with a sister who has a crush on the Kid. But the boys must also battle wits with a ranch owner who thinks that the horses walk on his land. Prhaps the only solution is to shoot him to stop him from stealing ""their"" horses?
After an embezzling banker / murderer sets up Curry and Heyes to take the fall for his crimes, the boys try to clear themselves by playing on his greed with a salted diamond field.
While Curry drives a wagonload of dynamite across rugged country, Heyes hires on as a guide for two Englishmen searching for a tribe of giant redheaded Indians rumored to have lived in the area of Devil's Hole.
After being chased for weeks by a posse, Heyes and the Kid hide out on a ranch where a nice but poor family lives. They become idols of sorts for the two daughters, and quickly learn to like all of them. Then, when the posse finally shows up and demand that Heyes and the Kid come out, Heyes suggests that the family collects the bounty rather than the posse. The posse reluctantly gives them up, and the leader of the posse will not leave their side. On the way to the nearest sheriff office, however, the remaining posse are attacked - by the daughters. Heyes and the Kid get away, but changes their mind when they realize that the family could get in trouble for their sake. They return, but how can they stay out of jail if they have to give their identities away to the judge?
Heyes and the Kid meet two men at a carnival - one of them a gold digger, the other a fast-drawing cowboy with a big smile. The gold digger likes the three of them, and makes them an offer. If they come with him and work in his mine, they can share the gold between the four of them. When they decide that they've got enough gold, though, the smiling man disappears with the gold, the horses, and all provisions. Now Heyes, the Kid and the gold digger must get back to civilisation to get their gold back. But can they ""persuade"" the smiling man to share his gold with them? And can the Kid out-draw him?