Painkiller Jane

The BEST episodes of Painkiller Jane

Every episode of Painkiller Jane ever, ranked from best to worst by thousands of votes from fans of the show. The best episodes of Painkiller Jane!

In a very imaginable future, the world battles terrorism and unrest. Out of this chaos emerges a new hero: Jane Vasco, a.k.a. Painkiller Jane Once the DEA's top agent, Jane Vasco is formidable, both mentally and physically. As a child, her father nicknamed her Painkiller Jane, describing her ability to mentally push through even the most painful situations. But her strength is about to be tested. Jane is recruited by a covert government agency dedicated to containing and, if necessary, neutralizing the threat of "Neuros" No one knows what caused the aberrations that led to their enhanced abilities, which range from from telekinesis and telepathic suggestion to induced hallucinations. During her first investigation with her new team, Jane discovers that she too possesses an odd ability: she can't be killed.

Last Updated: 6/1/2022Network: Syfy
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Something Nasty in the Neighborhood
star
8.13
16 votes

#1 - Something Nasty in the Neighborhood

Season 1 - Episode 12 - Aired 7/6/2007

Jane and Connor go undercover in a small town, posed as a married couple, after a federal agent's disappearance prompts an investigation.

Directors: Michael Robison
Watch Now:Amazon
What Lies Beneath
star
8.13
16 votes

#2 - What Lies Beneath

Season 1 - Episode 19 - Aired 8/31/2007

The team respond when several incarcerated Neuros revolt and launch a prison break.

Directors: Matt Hastings
Watch Now:Amazon
Endgame
star
8.12
17 votes

#3 - Endgame

Season 1 - Episode 22 - Aired 9/21/2007

Several dangerous Neuros launch a prison break after an emergency at NICO.

Directors: Farhad Mann
Watch Now:Amazon
Higher Court
star
8.11
28 votes

#4 - Higher Court

Season 1 - Episode 7 - Aired 6/1/2007

The team investigate the suicides of individuals placed in witness protection and discover a Neuro who is capable of creating hallucinations.

Directors: Matt Hastings
Watch Now:Amazon
The Beast of Bolnar
star
8.00
15 votes

#5 - The Beast of Bolnar

Season 1 - Episode 20 - Aired 9/7/2007

The residents of a small village are plagued by an invisible presence which is attacking and murdering the villagers.

Directors: Farhad Mann
Watch Now:Amazon
Reflections
star
8.00
14 votes

#6 - Reflections

Season 1 - Episode 21 - Aired 9/14/2007

Andre encounters a Neuro from his past that was chipped, but he learns that she has regained her abilities and she has a grudge.

Directors: Matt Hastings
Watch Now:Amazon
The Amazing Howie
star
7.85
20 votes

#7 - The Amazing Howie

Season 1 - Episode 14 - Aired 7/20/2007

Howie is a magician who can miraculously perform the impossible, which prompts Riley to begin an investigation into possible Neuro activity.

Directors: Matt Hastings
Watch Now:Amazon
Nothing To Fear But Fear Itself
star
7.83
36 votes

#8 - Nothing To Fear But Fear Itself

Season 1 - Episode 5 - Aired 5/11/2007

When inhabitants of an FBI safe house start to experience unexplained dreams and visions, Jane and crew must investigate potential Neuro activity.

Directors: Matt Hastings
Watch Now:Amazon
The Healer
star
7.81
16 votes

#9 - The Healer

Season 1 - Episode 15 - Aired 7/27/2007

Sabotage hinders Jane's efforts to catch a Neuro, she becomes suspicious of a faith healer that she has been visiting.

Directors: Michael Robison
Watch Now:Amazon
Jane 113
star
7.75
16 votes

#10 - Jane 113

Season 1 - Episode 18 - Aired 8/24/2007

Jane discovers the disturbing truth about her abilities while searching for a Neuro who escaped the team.

Directors: Peter DeLuise
Watch Now:Amazon
Portraits of Lauren Gray
star
7.73
26 votes

#11 - Portraits of Lauren Gray

Season 1 - Episode 10 - Aired 6/22/2007

A young woman suddenly ages overnight, Jane and Maureen go undercover to find the cause.

Directors: Peter DeLuise
Watch Now:Amazon
The League
star
7.71
21 votes

#12 - The League

Season 1 - Episode 13 - Aired 7/13/2007

An investigation is started after Neuros begin to die before the team can apprehend them.

Directors: Paul Ziller
Watch Now:Amazon
Friendly Fire
star
7.71
31 votes

#13 - Friendly Fire

Season 1 - Episode 8 - Aired 6/8/2007

Awakening in a hospital Jane learns that she murdered Riley. Meanwhile, Maureen investigates a doctor researching Neuros.

Directors: David Tennant
Watch Now:Amazon
Trial by Fire
star
7.62
26 votes

#14 - Trial by Fire

Season 1 - Episode 9 - Aired 6/15/2007

Connor is arrested for arson and murder while out hunting for a Neuro, which is believed to have started numerous house fires.

Directors: J.B. Sugar
Watch Now:Amazon
Ghost in the Machine
star
7.55
22 votes

#15 - Ghost in the Machine

Season 1 - Episode 11 - Aired 6/29/2007

Connor suffers a series of unfortunate events, believing it to be coincidental. However, he learns that members of his former police squad have died of strange causes.

Directors: Brent Clackson
Watch Now:Amazon
Catch Me if You Can
star
7.49
45 votes

#16 - Catch Me if You Can

Season 1 - Episode 4 - Aired 5/4/2007

A Neuro who can see the future warns Jane and the team of their impending death on the day they arrest him. Meanwhile, the team is disturbed by the psychic's purchases

Directors: Farhad Mann
Watch Now:Amazon
Piece of Mind
star
7.44
55 votes

#17 - Piece of Mind

Season 1 - Episode 3 - Aired 4/27/2007

A Neuro with the ability to steal memory and knowledge preys on Riley putting the security of the entire operation in jeopardy.

Directors: Michael Robison
Watch Now:Amazon
Breakdown
star
7.35
60 votes

#18 - Breakdown

Season 1 - Episode 6 - Aired 5/18/2007

While investigating psychiatric patients who share the same unusual nightmare, Jane and Maureen suspect a Neuro has the ability to use nightmares as weapons.

Directors: William Waring
Watch Now:Amazon
Playback
star
7.20
44 votes

#19 - Playback

Season 1 - Episode 17 - Aired 8/17/2007

A Neuro causes the team to become stuck in a timeloop, causing them to relive the same day repeatedly. Meanwhile, the Neuro who caused the timeloop tries to finish an assassination.

Directors: Matt Hastings
Watch Now:Amazon
Thanks For the Memories
star
7.17
18 votes

#20 - Thanks For the Memories

Season 1 - Episode 16 - Aired 8/3/2007

Jane seeks help from a Neuro after Brian (Jane's boyfriend) and Joe forget who she is, the Neuro has the ability to remove and store memories within his mind.

Directors: Charles Heit
Watch Now:Amazon
Pilot
star
6.91
230 votes

#21 - Pilot

Season 1 - Episode 1 - Aired 4/13/2007

Jane Vasco with the help of a new covert government unit must track down and contain the spread of "Neuros," genetically altered humans with extraordinary powers.

Directors: Nick Copus
Watch Now:Amazon
Toy Soldiers
star
6.66
143 votes

#22 - Toy Soldiers

Season 1 - Episode 2 - Aired 4/20/2007

When military stockpiles start to go missing before a presidential visit, Jane and the team are forced into high alert. Meanwhile, Jane confronts a Neuro with the ability to control the dead.

Directors: Michael Robison
Watch Now:Amazon

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