Darien Fawkes is a thief and conman with a scientist brother, Kevin. Kevin develops a gland that allows the implantee to excrete "Quicksilver" and turn invisible. Unfortunately, the gland has the side effect of rendering the implantee berserk if a counteragent isn't occasionally injected. Darien agrees to the operation to avoid a jail sentence. Terrorists kill Kevin, leaving Darien with the gland stuck in his head. A mysterious "Agency" was behind Kevin's research, and offer Darien a deal: work for them in return for injections of the Counteragent. Using his powers of invisibility, Darien takes on spies and other criminals for the government.
During an attempt to stop Chrysalis from testing a stolen laser that generates lightning, Darien is shocked and gets amnesia. He turns himself in to the police but they try to arrest him based on his criminal record. Stark, Chrysalis' leader, takes Fawkes away and tries to convince him he works for the CIA. However, the amnesiac Darien is stolen away a third time by the invisible Arnaud DeFehrn, who convinces Darien that he is his similarly-invisible brother Kevin, and that they have to rescue their third brother, Johnny. Johnny turns out to be Huiclov, DeFehrn's brother, and the whole thing is a ploy to get Huiclov out of prison. Darien manages to regain his memory and capture Arnaud only to give into Quicksilver madness, and DeFehrn escapes. Stark figures out there is a second invisible man and contacts DeFehrn to make an alliance to restore Arnaud's visibility...and kill Darien.
While getting his weekly Counteragent shot, Darien becomes infected with an experimental batch of Counteragent. The experimental stuff renders Darien randomly invisible...and it's contagious. First the Keeper becomes infected when she cuts herself while taking blood samples. She goes into Quicksilver madness, and attacks the Official. Both he and Hobbes becomes infected as well. Darien is also going into Quicksilver madness, since the arm with his tattoo is invisible. The Official locks down the facility under quarantine, but goes nuts as well, and escapes. Returning agent Alex Munro manages to capture him, and they discover that Hobbes is uninfected. The mayo on his sandwich was bad, and the bacteria counter-acted the experimental Counteragent. All they have to do to cure themselves is eat similar sandwiches with bad mayo...and get food poisoning for a couple of days.
Going to Mexico to investigate Arnaud, Bobby meets his new partner Bobby Hobbes: a veteran spy and near basket-case. They escape an ambush by French-Canadian spies. Meanwhile, Arnaud has had Darien's girlfriend Casey brought down to Mexico, planning on using her as a hostage. Darien goes to rescue her, prepared to kill Arnaud since Darien thinks he'll be going insane shortly. Arnaud plays his trump card: there's a counter-agent that will stave off Quicksilver madness, and he'll give it to Darien if he works for him. Darien refuses, escaping with Casey and blowing up the compound (although Arnaud escapes). Both the counteragent and the formula are destroyed, and Darien goes to visit his brother's grave one more time before going permanently insane. However, the Official meets him there and reveals that his Agency was working with Kevin, and they have the counter-agent as well. As long as Darien works for them, he'll get regular doses of the Counter-Agent. Reluctantly, Darien agrees.
The Agency is now controlled by the Department of Human Services. Quintuple-A rated agent Alex Munro comes barging in, taking control of the place. She knows everything about everyone, but her own record is murky. Her first case is to have the Agency investigate the disappearance of babies from hospitals. Fertility clinics owned by the same corporation are the key factor. The team prevents an abduction and tracks the abductor to a summer camp where children are being raised from birth and brainwashed by the Chrysalis organization. A standoff between the Agency and the armed children ensue, but Darien breaks the stalemate by entering the compound and calling for Chrysalis leader Stark. Darien convinces Stark to release the children rather then have them get killed. The children turn themselves in, but Stark escapes as part of the deal. It turns out that Alex's baby was one of the abductees...and her child isn't among the residents of the camp.Watch Now:Amazon
During a mission Darien gets a back injury, and the Official refuses to pay for treatment. Seeking out an accupuncturist, Darien inadverently reveals he can become invisible. On his next visit, the accupuncturist, Charlene, inserts needles that allow her to use electricity to put Fawkes in agony if he doesn't obey her. She needs a rare set of mystical needles to cure her mentor, and Darien to steal them. He succeeds, but the needles have ""bad chi"" because the original owner, a millionnaire, stole them. The millionnaire has to be killed to eliminate the bad chi, but Charlie can't do it without gaining bad chi. So she forces Darien to try. Needing Counteragent, Fawkes manages to leave a clue so that the Agency can follow them, and prevent the murder.
Darien goes undercover as a thief to infiltrate the gang of the mysterious terrorist Javier and discover why they are stealing random parts. He and the leader of the gang, Dante, are captured and sent to prison, where Fawkes is left there to try and get the info from Dante. Pressured by two cronies from his previous stay, Darien promises to get them out by using his invisiblity to steal the warden's nameplate. Dante, impressed, also goes along with him. Darien breaks Dante out, while Alex and Hobbes manage to find the remaining members of the gang. It turns out the components can form an EMP bomb, but while the team manages to capture the gang, Javier escapes.Watch Now:AmazoniTunes
Darien is approached by Tommy Walker, a man whose senses (except touch) have been rendered inoperative. Using a special chest-mounted sensor device, Walker can get around, and can even spot Fawkes when he's invisible. He claims that he was another of Kevin Fawkes' experiments. Walker shows Darien some of the other experiments with sensory-deprivation performed by Kevin and his partner, Augustin Gaither. The other subjects went insane. However, a mysterious government organization, the Secret Weapons Research Branch, break in and claim everything is under their jurisdiction: even the Official is intimidated. They take Walker prisoner, but Darien believes Tommy can lead him to Gaither, who may know about Kevin's experiments and can find a way to remove the gland. Fawkes rescues Walker from the SWRB, only to discover that he is Augustin Gaither: he was driven insane by the same process when he used it on himself, and now believes he is ""Tommy Walker"". The SWRB blow up Hobbes' house where
After an operation goes bad and Fawkes goes into Quicksilver Madness, Darien realizes that there may be a way to find a cure. Despite the Official's orders not to, he has the Keeper inject him with some of his brother Kevin's DNA and channel his personality and memories as he did with Simon Cole (in ""The Other Invisible Man""). The operation succeeds, but the DNA dates back to four months before Kevin and Arnaud DeFehrn mutated the gland. Hobbes and ""Kevin"" track down Dr. Elizabeth Rindell, who put the second gland in DeFehrn. DeFehrn beats them up and manages to escape, but ""Kevin"" is later kidnapped. ""Kevin"" fakes a fit of madness, knowing that the Counteragent will bring Darien back. Arnaud escapes again, but they get hold of a laptop computer with files on the gland. However, when they bring ""Kevin"" back for the last time to decipher the files, he refuses, believing Darien is a better person for it. Darien, needless to say, is less than thrilled.Watch Now:Amazon
Hobbes, Fawkes, and Alex go undercover since the Agency is now under the Post Office. They are sent to investigate thefts from the dead-letter office. When Hobbes opens an envelope with a card that plays ""Jingle Bells"", he goes berserk and shoots up the place. All of the team undergo psychiatric evaluation, but the only consistent factor in all their stories is the card. When Eberts opens it, he goes berserk as well. It turns out the card has a touch-transmitted chemical in it that, in conjunction with the song, turns the victim into a berserker. The card was sent to the post office by some 60's anti-establishment type and was leftover until someone found it. Fawkes manages to stop Eberts, and Hobbes is given a clean bill of health.
Fawkes, Hobbes, and Alex are sent to bring in a kid, Adam Reese, for testing. After thwarting a Chrysalis attack, Alex explains that Adam has an Ebola-like retrovirus as part of a government experiment that will become active when he hits puberty. Darien manages to convince Adam to come in for the tests anyway. Unfortunately, the government simply plans to incinerate Adam. Hobbes and Fawkes help Adam escape, and manage to steal a cyrogenic pod (last seen in Frozen in Time) from Chrysalis. Adam goes into suspended animation rather then unleash the virus.
Hobbes and Darien investigate a hacker trying to break into the Agency computer system. The hacker escapes, and Eberts manages to suggest being allowed to tag along with the team as a computer expert. He and Fawkes sneak into a internet cafe but are ambushed. Knocked out from behind, Eberts is taken back to the Agency and soon starts to act increasingly aggressive, going so far as to ignore the Official when inevitably told to ""Shut up, Eberts!"". Eventually Hobbes and Fawkes discover that Ebert has been replaced by their invisible nemesis Arnaud DeFehrn. DeFehrn gained cell samples of Eberts during his last physical, and used them to make up a lifelike skin mask. He needs Eberts' access to get into the Official's computer. After a bicycle & skateboard chase, DeFehrn manages to elude Darien, leaving the Agency to wonder when DeFehrn will show up again.
Hobbes and Darien meet with one of Hobbes' contacts to set a trap for their arch-enemy, Arnaud. Arnaud manages to escape Darien with the aid of a smoke canister, which turns out to contain a biological weapon. Darien is soon displaying flu-like illness symptoms, and is excreting black, contaminated Quicksilver. The Official and the Keeper send him to a military hospital...which Arnaud has already infiltrated. He plans to remove the Quicksilver Gland from Darien's skull via surgery, but the illness complicates matters. He must kidnap the Keeper to cure Darien so he can gain an uninfected Gland. Darien manages to escape and, overwhelmed by madness, almost kills Arnaud. The Keeper manages to stop him but Arnaud escapes. (Copyright 2002 Steve Crow)
Kate Easton (The Value of Secrets) is on the run from Allianora. Easton is grabbed before Darien can get her to safety and put into cyrogenic suspension by Allianora's (as yet unidentified) employers. The people Allianora work for are collecting scientists for future use under their control. The Agency manages to capture Allianora, but she proves impossible to crack. So Darien secretly cuts her a deal: he'll betray the Agency and help her escape if she'll betray her bosses and help him rescue Kate. Both of them end up double-crossing each other, and Darien ends up in a cyrogenic tube when Allianora scrambles his tracking signal. He manages to escape using his invisibility and rescue Kate. However, when he returns with the Agency, the warehouse and the remaining scientists are gone.
A series of bizarre killings involve murderers who have no connection to the victims. The Keeper becomes the next unwitting "murder," as she is part of a insomnia-research project. The project's scientists are using the device to program their subjects to become assassins. The Keeper's sanity is threatened if she can't complete her "assignment." Fawkes and Hobbes eventually mange to bring in the scientists, and come up with a means to break the Keeper of the programming (by faking the death of her "victim") before she goes mad.
Hobbes and Darien are on the trail of a sperm thief. A college professor is using the sperm to isolate intelligence-causing genes, and put them into a retrovirus. Hobbes is accidentally infected and soon begins to become more and more intelligent. But the partners discover that the gene therapy is lethal. Bobby becomes smart enough to create a cure...but refuses to do so, preferring to die smart then live dumb. Darien infects himself, leaving Hobbes no choice but to come up with a cure to save his friend.
Darien, the Keeper and Hobbes head south of the border to Santa Ruego to convince the Prime Minister to vote against installing the Biox chemical weapon system. How? By having Fawkes pretend to be a ghost and persuade the superstitious Minister to vote against the system's installation. Unfortunately, another "spirit" is haunting the Minister: "La Llarona," a ghost who can drown men with a kiss. She confronts Darien and it is revealed she is a member of a shadowy organization that bio-engineered her with the ability to breathe water and exhale it under pressure. In the battle over the Prime Minister's vote, Darien eventually manages to drive her off and get the vote, despite the mutual attraction the two "freaks" share.
A ghoulish hitman uses a laser to blind any witnesses to his killings. Fawkes and Hobbes trace him to a blind model who the killer is romantically involved in, but the assassin escapes, blinding Fawkes in the process. Since he was turning invisible when the laser hit him, the effects are temporary, and he can still see if he covers his eyes with the quicksilver formula. Unfortunately, that aggravates his growing insanity. The blind model helps him to deal with his blindness, and the two become romantically involved. Fawkes figures out that the assassin's most recent victim was merely a lure to get his real victim to the man's funeral. Fawkes, overwhelmed by Quicksilver Madness, throws the assassin to his death.