Kitty and Matt are off for St. Louis, until Matt is summoned back on business. Upset with him, Kitty sets off for herself meeting a gunslinger on the stage who ends up saving her life. He goes back to Dodge with her and proceeds to court her. Kitty has a hard decision. Leave Matt after 18 years of a relationship or stay with Stambridge.
Matt is on the trail of a badly wounded corporal for robbing the army payroll and falls into a trap when the father of the corporal gets the drop on him and wounds Chester.
When a young teenager from a group of squatters decides he can do better than stealing, he changes his ways. But the leader of the squatters will try to manipulate the young man with the people that has treated him the best.
The Osage Council has found Two Bears guilty of murder. His daughter rides into Dodge seeking Matt's help but he's out of town chasing horse thieves so Thad tries to help. He finds out that he and Matt are really riding the same trail.
After a young man kills a gunfighter he becomes the victim of publicity.
Newly falls in love with a woman who could put him in danger, once her past is known.
When hired gunman Killion comes to Dodge, many of the men get scared thinking he is after them, but it turns out his paid target is a woman.
A bank robber hides out in Dodge, bringing along his girl. While he's gambling away his loot, his girl casts her eye on Matt.
A young boy comes to Dodge looking for his father. What he finds is that his father is a wanted outlaw on the run.
Matt rescues teen-aged Trudy Trent from a life of isolated poverty with her incestuous and alcoholic father, but he subsequently learns that "Hell hath no fury like a woman scorned" when he rejects her misguided romantic overtures toward him.
With a well earned vacation disturbed by the arrest of a hardened criminal, Matt and Kitty head back to Dodge. The stage they are on is sabotaged and end up wrecking. Kitty is quick witted enough to switch identities between Matt and the prisoner before the outlaws get to them. Thinking Dillon is dying and Matt is really Monk Wiley, they go on planning to extort money from Dodge to get Dillon back alive.
Leary O'Quillan kills a card cheat in self defense and is pursued to Dodge by the man's brother, Clay Tynan.
Sergeant Holly, a alcoholic loving veteran is getting ready to retire. Just hours before it, a Apache prisoner in his custody escapes with Kitty as a hostage, forcing the Sergeant to go AWOL to get the prisoner back.
Fast gunman Jim Barrett kills a man in self defense. Now the man's father and brothers are gunning for him, in addition to a young man who wants Barrett dead for a different reason.
A young drifter takes a job as cook at Delmonico's but accidentally kills a crazy buffalo hunter who complains about his cooking.
Matt and former outlaw Elihu Gorman go after Dobie Price who has just broken jail.
Festus, in the desert hunting escaped killer Gard Dixon is wounded by the outlaw. He is found by Ben Snow, a half-crazy hermit who has been living in the desert with his gold for many years.
A man who persuaded the good folks of Dodge to invest their money in a mine is out of prison and back to prove that there really is gold in the mine.
After a risky train robbery and with two posses on their trail, four men hurriedly ride to some fresh horses. Dillon wounds one of the gang carrying the stolen money and it turns out to be a young woman.
An orphan steals from Matt but could risk his own life when he tries to help out in an ambush.
Matt, Festus and Newly attempt to rescue Doc and Lyla from Shindrow's camp.
Matt is in Mexico to pick up a wanted criminal. When bandits steal his credentials, they spring the criminal with the idea of forming a gang of violence.
A band of robbers have hit numerous banks with uncanny precision, planning and ease. They have their sights on Dodge now but they must remove a big obstacle before they can proceed - Marshal Dillon.