The BEST episodes of The Tonight Show with Jay Leno season 16

Every episode of The Tonight Show with Jay Leno season 16, ranked from best to worst by thousands of votes from fans of the show. The best episodes of The Tonight Show with Jay Leno season 16!

The Tonight Show with Jay Leno is an American late-night talk show currently hosted by Jay Leno, on NBC. It made its debut on May 25, 1992, following Johnny Carson's retirement as host of The Tonight Show. The nightly broadcast at 23:35 (Eastern) originates from NBC's studios, in Burbank, California.

Last Updated: 11/10/2024Network: NBCStatus: Ended
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#1 - John Larroquette, Chelsea Handler, Matchbox Twenty

Season 16 - Episode 73 - Aired 10/4/2007

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#2 - Samuel L. Jackson

Season 16 - Episode 13 - Aired 6/20/2007

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#3 - Jonah Hill, Michael Cera, Christopher Mintz-Plasse, Mo Rocca, Jarod Miller, Wilco

Season 16 - Episode 49 - Aired 8/30/2007

Cast of Superbad

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#4 - Robin Williams, Chelsea Handler, Big & Rich

Season 16 - Episode 11 - Aired 6/18/2007

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#5 - Bill Cosby, Avril Lavigne

Season 16 - Episode 10 - Aired 6/15/2007

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#6 - Tea Leoni, Joy Behar, Bloc Party

Season 16 - Episode 9 - Aired 6/14/2007

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#7 - Terry Bradshaw, Shia LaBeouf, James Morrison

Season 16 - Episode 8 - Aired 6/13/2007

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#8 - Fred Thompson, Lauren Graham, Toby Keith

Season 16 - Episode 7 - Aired 6/12/2007

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#9 - Wanda Sykes, John Mayer

Season 16 - Episode 6 - Aired 6/11/2007

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#10 - Steve Carell, Kenny Smith, Goo Goo Dolls

Season 16 - Episode 5 - Aired 6/8/2007

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#11 - Don Rickles, Josh Flitter, Dashboard Confessional

Season 16 - Episode 4 - Aired 6/7/2007

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#12 - Bernie Mac, Cat Deeley, Chris Cornell

Season 16 - Episode 3 - Aired 6/6/2007

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#13 - George Clooney, Rihanna

Season 16 - Episode 2 - Aired 6/5/2007

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#14 - John Cusack, Tavis Smiley, Lifehouse

Season 16 - Episode 14 - Aired 6/21/2007

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#15 - Tom Selleck, Carlos Mencia, Bobbie and Willie Nelson, Ed Asner

Season 16 - Episode 72 - Aired 10/3/2007

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#16 - Bill Cosby, Landon Pigg

Season 16 - Episode 125 - Aired 3/12/2008

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#17 - America Ferrera, Bob Saget, The Blind Boys of Alabama

Season 16 - Episode 124 - Aired 3/11/2008

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#18 - Dominic Monaghan, Ethan Bortnick, Sheryl Crow

Season 16 - Episode 97 - Aired 3/10/2008

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#19 - Gordon Ramsay

Season 16 - Episode 78 - Aired 10/11/2007

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#20 - Brad Garret; Ingrid Michaelson; John Melendez

Season 16 - Episode 126 - Aired 4/15/2008

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#21 - Anne Hathaway; Gabriel Iglesias; Amos Lee

Season 16 - Episode 139 - Aired 6/16/2008

Ryan Phillippe; Lisa Lampanelli; Jim Lauderdale
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#22 - Ryan Phillippe; Lisa Lampanelli; Jim Lauderdale

Season 16 - Episode 140 - Aired 3/19/2008

Ryan Phillippe from "Stop-Loss", Lisa Lampanelli from "Drillbit Taylor" and music of Jim Lauderdale from the CD "Honey Songs".

Dave Salmoni; Patricia Arquette; Punch Brothers
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#23 - Dave Salmoni; Patricia Arquette; Punch Brothers

Season 16 - Episode 132 - Aired 2/29/2008

Amazing animals with Dave salmoni! From "medium" Patricia Arquette! The music of Punch Brothers! " Jaywalking."

Dana Carvey; Malin Akerman; Plain White T's
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#24 - Dana Carvey; Malin Akerman; Plain White T's

Season 16 - Episode 77 - Aired 10/10/2007

Dana Carvey; Malin Akerman ("The Heartbreak Kid"); Plain White T performs from the CD "Every Second Counts."

Jamie Pressly; Brady Barr; Blue Man Group
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#25 - Jamie Pressly; Brady Barr; Blue Man Group

Season 16 - Episode 76 - Aired 10/9/2007

Jamie Pressly ("My Name is Earl"); National Geographic's Brady Barr; Blue Man Group performs.