Tough, no-nonsense private eye Joe Mannix investigates in this tense and violent detective series. Originally employed by an ultra-computerized organization, he later set up his own shop. But mayhem always predominated.
Mannix tries to solve the murder of a newspaper columnist, and finds himself dealing the deceast's deranged daughter. She was an eyewitness to the crime but when Mannix tries to get information from her, he plays psychotherapist to get the facts from her.
The strong friendship between Lew Wickersham and Mannix melts into a violent and deathly feud. The bitter battle begins when Mannix launches an investigation into the theft of a highly secret formula for the development of a laser ray. Stolen plans and sabotage involve Intertect and their agents.
An escaped convict saves Mannix's life.