Ben Matlock is a very expensive criminal defense attorney who charges $100,000 to take a case. Fortunately, he's worth every penny as he and his associates defend his clients by finding the real killer.
When Leanne's ex-husband Peter is charged with the murder of his friend and boss, once the truth comes out about Peter's possible motive in the killing, Matlock despises his ex-son-in-law more than ever.
Ben is hired by a friend to defend his son, who is in the army, who's been charged with killing the sadistic lieutenant, whose mistreatment of his men led to the death of his friend.
Cliff gets entangled in the case of his old college buddy, a defense attorney being blackmailed to sabotage his current case. But when the blackmailer turns up dead and Cliff stands accused, it's Matlock to the rescue.
Amy Adler had a juvenile record before becoming a photographer's assistant. When the photographer she works for is murdered, she begs Matlock to help her out. While pro bono cases aren't usually his style, something about the feisty young woman catches his interest, and he agrees to help her out.
When a gambler is accused of killing his bookie, Matlock agrees to take the case, believing that someone from the bookie's past is the guilty party.
When Billy Wheeler comes back to town $250,000 richer after having won the lottery, he soon falls for contractor Judy Wilson. Unfortunately, when she takes him and every other partner for a ride, Billy is accused of her murder, and Matlock has to clear his name.
After he's conned by a group of con men, Brian Davis is accused of murdering one of them. Matlock agrees to take on the case, and while Michelle tries to get close to one of the remaining con artists, Matlock tries to prove that a previous scheme is responsible for the current predicament.
Catherine McKay is an aging prima donna who only had one hit movie in her career. When she's found dead, stabbed in the chest with the knife that made her famous, suspicion lands on Noel Bishop, the horror film director that wanted her off his picture.
Marvin Sheam and Sid Franklin have been in business for 32 years. When their bank loan is denied and they can't pay their bills, Marv tries to talk Sid into hiring an arsonist to torch their business so they can collect the insurance money and rebuild from scratch. Just before Marv has a chance to talk to the arsonist again, he winds up dead outside his daughter's wedding reception, and Sid gets blamed.
When Matlock's nephew Irwin is charged with murder, Matlock investigates at a high-tech computer firm to clear his name.
Matlock agrees to defend a psychic, Jennifer Holtz, who claims to have seen the murder before it ever took place.
When talk show host Dan Galloway is murdered after publicly humiliating three woman on the air and firing his executive producer, there is no shortage of suspects. Nearly everyone who ever met the man wanted him dead, but it's up to Matlock to prove whether Marla, Leanne or Katherine committed the crime as he tries to prove that his own client, Lisa, did not.
Matlock has to defend an arrogant young tennis professional (Dave Travis) against a charge of murdering his rival on and off the court (Victor Tomassio).
When the local mayor is assassinated, Matlock's daughter Leanne comes to town to prove the case. The case takes a different turn when a judge is accused of murdering a local man's wife, and Ben and Leanne have to work out the problems in their relationship to clear Eller of murder.
Matlock and Leanne head to the beach where Leanne reunites with three good friends from college, and Matlock reunites with someone from his past who just happens to be the brother of the woman whose heart Matlock 'broke' years earlier.
Matlock agrees to defend a man who has been accused of murdering the relationship columnist whose response ended his relationship.
Matlock tries to prove that someone other than his client had a motive to murder his lover. His best bet? The victim's paraplegic husband.
After her husband's death she never thought she'd love again, but it Bonnie soon found her future with Cal Ritter. The only problem is that her son, Tony Morgen, hates Cal. When Tony kills Cal and frames his mother for her murder, Matlock takes the case to prove that Bonnie is innocent, but to prove her innocence, he will have to destroy her son.
Matlock has finally had the breakthrough in the case he was struggling with, but after being hit by a car, he needs to put the case together from scratch. Unfortunately, his nurse isn't too pleased to see him trying to work, and does her best to make sure he gets the rest he needs.
When William Austin comes to Atlanta from Chicago and heads to the cult that has ensnared his son Dennis, Dennis tells him to leave him alone, the cult is his home now, and that he is no longer his father. The leader of the cult, Joshua Bradbury, tells Austin that he needs to accept Dennis' decision, and to leave him alone. Austin refuses to leave without his son, and Bradbury has the police escort Austin (who threatens to take off Bradbury's head) out of mansion. Dennis observes someone shooting Joshua, then tells police he sees his father fleeing the scene of the crime. William Austin heads to Ben Matlock for help in defending himself. After learning that Dennis has signed his trust fund and his life's savings over to the cult, Matlock confronts him, and is shocked to hear Dennis deny his father. Matlock goes to a reknowned expert in de-programming cult victims, who tells him that Dennis may believe he saw his father, but he is probably so brain-washed by the cult that he can't real
When a scrooge of a store owner is accused of murdering his partner for being 'good' at Christmas, Matlock agrees to take the case, but Steven Abbott is furious when part of Matlock's fee involves Abbott having to be a 'good' guy.
Michelle agrees to defend college chum Andrea Morrow after she is accused of murdering her abusive lover, Clay Graham. Matlock soon becomes convinced that the murderer was Clay's blind 'friend', Arthur Hampton, but will have a devil of a time proving how a blind man managed to carry off a near-perfect murder.
Matlock agrees to defend Vanessa Douglas when she's accused of murdering Stephen Cassidy, and author who destroyed a political families ambitions with a tell-all book. When Matlock realises his client is indeed guilty of the murder she is charged of committing, he sets up a plan to implicate her best friend, Sarah, with the crime, knowing that Vanessa will not let her friend take the blame for something she did.
When a down-on-his luck Santa Claus (Tom McCabe) is accused of killing the landlord who was about to evict not only him but everyone else in the apartment complex, the people in his building take up a collection and come to Matlock to ask him to defend him. They may not like Tom, but none of them believe him guilty of murder. Matlock ignores his own misgivings about a man he can't help but dislike and agrees to defend Tom.
With Angela's help, Conrad tries to track down an informer they believe holds the key to Sam Chandler's murder.