The BEST episodes of B Positive

Every episode of B Positive ever, ranked from best to worst by thousands of votes from fans of the show. The best episodes of B Positive!

Drew is a therapist and newly divorced dad who is faced with finding a kidney donor when he runs into Gina, a rough-around-the-edges woman from his past who volunteers her own. Together, they form an unlikely and life-affirming friendship, as they begin a journey that will forever affect both of their lives.

Last Updated: 11/2/2026Network: CBSStatus: Ended
Heartburn, Woodstock and Ribs
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#1 - Heartburn, Woodstock and Ribs

Season 2 - Episode 9 - Aired 1/6/2022

Drew returns from his road trip to be with Gina and the retirement home residents and staff and mourn the death of a beloved friend.

Directors: Richie Keen
Love, Taxes and a Kidney
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#2 - Love, Taxes and a Kidney

Season 2 - Episode 1 - Aired 10/14/2021

As Gina and Drew adjust to life after surgery, Drew develops romantic feelings for someone new, and Gina gets surprising news about a friend’s death.

Directors: James Widdoes
Vermont, Switzerland and Connecticut
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#3 - Vermont, Switzerland and Connecticut

Season 2 - Episode 2 - Aired 10/21/2021

Gina and Eli's relationship is tested by Gina's new wealth. Also, Drew gets a surprise visit from his long-distance girlfriend, Adriana.

Directors: James Widdoes
Bagels, Billiards and a Magic Show
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#4 - Bagels, Billiards and a Magic Show

Season 2 - Episode 3 - Aired 10/28/2021

On Gina's first day as the new owner of the retirement home, she asks Drew for help getting through to a short-tempered resident whose wife is sick.

Directors: James Widdoes
Baseball, Walkers and Wine
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#5 - Baseball, Walkers and Wine

Season 2 - Episode 4 - Aired 11/4/2021

Gina comes up with a plan to help a resident, Meredith, get some space from her overprotective husband. Also, Drew works up the courage to tell Gina he has feelings for her.

Directors: Phill Lewis
Novocaine, Bond and Bocce
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#6 - Novocaine, Bond and Bocce

Season 2 - Episode 5 - Aired 11/11/2021

Gina tries to convince Jerry to move into the senior center after he faints at work. Also, Drew and Gina deal with the emotional fallout of their drunken night out.

Directors: Phill Lewis
A Dishwasher, a Fire and a Remote Control
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#7 - A Dishwasher, a Fire and a Remote Control

Season 2 - Episode 6 - Aired 11/18/2021

Gina is pressured by the seniors at Valley Hills to fire the chef, Bert. Also, a frustrated Drew blows up at one of his therapy patients.

Directors: Phill Lewis
A Camper, a Compass and a Cannoli
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#8 - A Camper, a Compass and a Cannoli

Season 2 - Episode 7 - Aired 12/2/2021

Gina brings her dog Cannoli to the retirement home where he bonds with the seniors. Also, Drew prepares for his new life driving cross country in a camper van.

Directors: Richie Keen
A Dog, a Mousse and a Bat
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#9 - A Dog, a Mousse and a Bat

Season 2 - Episode 8 - Aired 12/9/2021

Gina promises to help Harry give his ailing wife a special anniversary dinner. Also, Drew connects with a charming young woman while on the road.

Directors: Richie Keen
Life Expectancy
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#10 - Life Expectancy

Season 1 - Episode 18 - Aired 5/13/2021

Before their surgeries, Gina looks for a new apartment while Drew celebrates his last day of dialysis.

S'mores, Elvis and a Cubano
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#11 - S'mores, Elvis and a Cubano

Season 2 - Episode 10 - Aired 1/13/2022

Gina gets a surprise visit from her sister, Natalie. Also, Drew and Harry start a road trip together, but have different destinations in mind.

Directors: Scott Ellis
Watch Now:Apple TV
Louisville, Bubbaroo and Sully
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#12 - Louisville, Bubbaroo and Sully

Season 2 - Episode 11 - Aired 1/20/2022

Gina hires Peter's son to be her lawyer, but things get complicated when he asks her out. Also, Drew and Harry's van breaks down during their road trip, leaving them stranded.

Directors: Scott Ellis
Dagobah, a Room and a Chimney Sweep
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#13 - Dagobah, a Room and a Chimney Sweep

Season 2 - Episode 12 - Aired 1/27/2022

Gina is overwhelmed when all the seniors at Valley Hills compete for a fancy upgraded room. Also, Drew and Harry finally arrive at the Grand Tetons, but Drew doesn't have the epiphany he hoped for.

Directors: Scott Ellis
A Boss, a Bear Claw and a Defibrillator
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#14 - A Boss, a Bear Claw and a Defibrillator

Season 2 - Episode 13 - Aired 1/27/2022

Gina struggles with being both a boss and a friend to Gabby and Gideon; Drew volunteers to drive the Valley Hills van; and Jerry learns he's healthy enough to leave Valley Hills.

Directors: Scott Ellis
Osteoporosis, a Thaaang, and a Slinky
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#15 - Osteoporosis, a Thaaang, and a Slinky

Season 2 - Episode 14 - Aired 2/24/2022

Gina gets caught in the middle when Norma's rude sister, Irene, arrives at Valley Hills. Also, Harry sets up Drew on a date, and Spencer and Bette take the next step in their relationship.

Directors: Scott Ellis
Payroll, a Waterwall and Valley Forge
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#16 - Payroll, a Waterwall and Valley Forge

Season 2 - Episode 15 - Aired 3/3/2022

Gina struggles to keep Valley Hills running smoothly after Mrs. Ludlum quits and starts work at a rival assisted living facility. Also, Drew wonders whether he should go on another road trip adventure or stay close to Gina.

Juneau, Froyo, and Mario Kart
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#17 - Juneau, Froyo, and Mario Kart

Season 2 - Episode 16 - Aired 3/10/2022

Gina is torn after getting an offer to sell Valley Hills to a rival assisted living residence. Also, Drew prepares to leave on his big trip to Alaska.

Directors: Phill Lewis
B Negative (2)
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#18 - B Negative (2)

Season 1 - Episode 10 - Aired 3/4/2021

Drew falls into a deep depression after a friends failed kidney surgery, and its up to Gina to help him out of it.

Watch Now:Apple TV
Die Alysis
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#19 - Die Alysis

Season 1 - Episode 2 - Aired 11/12/2020

When Drew's condition worsens, he needs to make sure Gina is still serious about donating her kidney and winds up making her an offer she can't refuse.

Directors: James Burrows
Foreign Bodies
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#20 - Foreign Bodies

Season 1 - Episode 3 - Aired 11/19/2020

As Gina makes herself at home in Drew's house, Drew begins to question whether he made the right decision.

Directors: James Burrows
Joint Pain
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#21 - Joint Pain

Season 1 - Episode 4 - Aired 12/3/2020

After Drew goes through a rough divorce mediation with Julia, Gina gives him a surprise to boost his spirits.

High Risk Factor
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#22 - High Risk Factor

Season 1 - Episode 5 - Aired 12/17/2020

Drew downloads a tracking app to keep an eye on Gina after he begins getting concerned about her reckless behavior.

Directors: Richie Keen
Open Heart Surgery
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#23 - Open Heart Surgery

Season 1 - Episode 6 - Aired 1/21/2021

Gina needs to keep herself together to pass a psych evaluation while dealing with the news of an ex's engagement.

Directors: Scott Ellis
Watch Now:Apple TV
Phantom Limb
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#24 - Phantom Limb

Season 1 - Episode 7 - Aired 2/11/2021

After missing Maddies soccer game due to dialysis, a depressed Drew begins to question if all his sacrifices are worth it.

Directors: Scott Ellis
Watch Now:Apple TV
Integration Therapy
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#25 - Integration Therapy

Season 1 - Episode 8 - Aired 2/18/2021

Drew realizes he lost all of his friends after his divorce, which prompts Gina to throw a party for his dialysis group.