The continued adventures of the Portokalos family from the film "My Big Fat Greek Wedding", starting when Nia and her husband return from their honeymoon.
After being teased by Nia, Thomas and Nikki. Nick decides to move into his own apartment, when Maria learns that her son has moved she has no one to comfort anymore, Nia tells her mother to take up a hobby, she ends up crowding Nia and Thomas by cleaning their house, and she ends up driving the rest of the family up the wall. When Nick spends a lonely night in his apartment, and inviting everyone over, he tells that he's moving back home because he misses the loudness of his family.
Nia is suspicious of her father giving Officer Joe free lunches, she believes that Gus is being blackmailed, so she gets the officer to pay for his food, Nia then realizes that her father and Joe have an arrangement(free lunches for a double parking space,) so she goes to City Hall to apply for a zoning permit, when the clerk is about to lose her cool with Nia, she eventually gets the permit with one exception (lunches for the clerk.)
In the opener, which backtracks from the film, the newlyweds arrive from their honeymoon in, where else, Greece, to an overwhelming family reception and news that Gus (Michael Constantine) has given them a generous gift â€” a house.
When Nia throws the Easter family dinner, she even invites her father's oldest friend, Constantine Christakos. When Nia realizes that Gus hates the man more than life itself, it's up to her to fix things before they ruin Easter. It turns out Gus says he stole his recipe for his famous feta omelet at dinner when Constantine toasts Gus. When he said "I accept your apology", they go at it, and it's up to Thomas to fix things. They eventually resolve their differences. When Maria accidentally spills that Constantine and her went out on a few dates, thinking that was the reason for Gus's 40 year hatred for him, they start up again and Nia is stunned when she learns that her mother used her lamb for the feast.
Cousin Ariana visits from Greece and announces that she has left her husband Dimitri because of him cheating with his (buck-toothed whore). So Nia decides to meddle in helping find Ariana a job with Nikki and Aunt Voula's help, Gus and Maria have the same idea in playing matchmaker with a Greek-American named, Spiro, Nia think's he's no good for her, leading Ariana to reveal that she likes Spiro, forcing Nia to admit to her father and the rest of the family that she was wrong.