Set in Chicago, Illinois, the series follows two people, Mike Biggs, a police officer who wants to shed some pounds, and Molly Flynn, a fourth-grade teacher wanting to embrace her curves, who meet at an Overeaters Anonymous group and become an unlikely pair. However, they also have to deal with the comments, jokes, and criticism from Mike's fast-talking partner Carl McMillan, Molly's slim, drug addicted sister Victoria and nymphomaniac mother Joyce, and Samuel, a Senegalese waiter at the officers' favorite restaurant.
In the series finale, Mike and Molly and the family have an impromptu gathering to reminisce about everything that has gotten them to this point, complete with a final fight between Joyce and Peggy.Watch Now:Amazon
Molly urges Mike to go to the doctor when she learns he hasn’t been in over a decade, on the 100th episode of MIKE & MOLLY.Watch Now:Amazon
A suddenly supremely confident Molly doles out advice to friends and family, including Samuel who contemplates doing stand-up comedy, and Harry whom she counsels to stand up to his protective mother.Watch Now:Amazon
Mike is forced to arrest Joyce for a DUI after she refuses to take a breathalyzer at a checkpoint.Watch Now:Amazon
Carl and Samuel hope for a little luck o' the Irish when it comes to picking up women at their St. Patrick's Day party, while Molly does a little Erin go bragging when she tells Mike about some of her holiday shenanigans.Watch Now:Amazon
On Valentine's Day, Mike and Molly play Cupid and prod Harry into asking Victoria out on a date, and to everyone's surprise she accepts. Meanwhile, Carl has a list of reasons why hanging out at the coin laundry on the holiday will help Samuel and him meet single women.Watch Now:Amazon
Mike is forced to set up his mom with his boss, despite his many reservations.Watch Now:Amazon
Molly looks to win some extra cash when she and the girls head to a riverboat casino for the weekend. Meanwhile, Mike and Vince try to enjoy some college basketball when the guys come over to watch TV.
Mike and Molly need everyone to be on their best behavior when the adoption agency schedules a home visit.Watch Now:Amazon
Molly decides to take a break from writing her novel and accepts a job as a forklift driver at Vince's warehouse, with mixed results.Watch Now:Amazon
Joyce conveniently disappears after a back injury renders Vince practically immobile, and that leaves Mike and Molly to take care of him. Meanwhile, the newlyweds are still laboring over personalized thank-you notes for their wedding presents.
Mike and Carl get stuck working at the Renaissance Faire after their boss, Patrick, gets dumped by Mike’s mother. Later, as a tornado descends on Chicago, Mike and Molly each confess important news to each other.