The BEST episodes of House season 5

Every episode of House season 5, ranked from best to worst by thousands of votes from fans of the show. The best episodes of House season 5!

Dr. Gregory House is a maverick physician who is devoid of bedside manner. While his behavior can border on antisocial, Dr. House thrives on the challenge of solving the medical puzzles that other doctors give up on. Together with his hand-picked team of young medical experts, he’ll do whatever it takes in the race against the clock to solve the case.

Last Updated: 8/29/2024Network: FOXStatus: Ended
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Both Sides Now
star
8.41
4030 votes

#1 - Both Sides Now

Season 5 - Episode 24 - Aired 5/11/2009

House and the team are intrigued by Scott, a man whose left brain and right brain operate independently, leaving him with two distinct personalities and no control over some of his actions. As the two sides of Scott’s brain struggle for dominance, his warring personalities make it increasingly difficult for the team to figure out what is causing the unique problem. The team is forced to use some unusual methods to get him to cooperate with their necessary testing. Meanwhile, when House refuses to make an appearance in the clinic, Cuddy takes an unconventional approach to force House to make up the time with a particular patient.

Directors: Greg Yaitanes
Writer: Doris Egan
Watch Now:AmazonApple TV
Under My Skin
star
8.02
3764 votes

#2 - Under My Skin

Season 5 - Episode 23 - Aired 5/4/2009

House and the team take on the case of a ballerina whose lungs collapse in the middle of a performance. When the treatment causes her skin to fall off, the dancer faces not only the prospect of never dancing again but also of dying an agonizing death. The team must use their imaginations to carefully choreograph ways to test and treat her delicate body without killing her. Meanwhile, House continues to suffer from what he thinks is insomnia, and he is willing to go to desperate measures to cure it.

Directors: David Straiton
Watch Now:AmazonApple TV
Simple Explanation
star
7.99
3385 votes

#3 - Simple Explanation

Season 5 - Episode 20 - Aired 4/6/2009

Charlotte, an older woman who has spent the last six months taking care of her dying husband Eddie, is rushed to Princeton Plainsboro after collapsing from respiratory failure. The couple becomes a double mystery for the team when Eddie begins to improve as Charlotte’s condition worsens. The previously unthinkable becomes real when it seems that Charlotte will die before Eddie, and the team will be forced to make a difficult decision.

Directors: Greg Yaitanes
Writer: Leonard Dick
Watch Now:AmazonApple TV
Locked In
star
7.93
3249 votes

#4 - Locked In

Season 5 - Episode 19 - Aired 3/30/2009

A man awakens in New York after a bicycle accident unable to move or communicate in any way. House, himself injured in a motorcycle mishap, occupies the hospital bed next to Lee and quickly annoys the doctors treating them both by insisting that Lee has “locked-in” syndrome.

Directors: Daniel Attias
Watch Now:AmazonApple TV
Last Resort
star
7.85
3254 votes

#5 - Last Resort

Season 5 - Episode 9 - Aired 11/25/2008

A man seeking the right diagnosis for his illness is willing to take on the hospital and the SWAT team to get it. He takes thirteen and several patients from the waiting room and puts them in Cuddy's office. To put an end to the crisis they must come up with the right diagnosis, treat the wounded, and hold off a SWAT team.

Directors: Katie Jacobs
Watch Now:AmazonApple TV
The Social Contract
star
7.80
3256 votes

#6 - The Social Contract

Season 5 - Episode 17 - Aired 3/9/2009

House and the team take on the case of Nick, a book editor who loses his inhibitions. The team realizes Nick has frontal lobe disinhibition, which causes him to speak his mind having no control over what he says and making him just like House. Meanwhile, House suspects Wilson and Taub are keeping something from him.

Directors: Andrew Bernstein
Writer: Doris Egan
Watch Now:AmazonApple TV
Let Them Eat Cake
star
7.78
3211 votes

#7 - Let Them Eat Cake

Season 5 - Episode 10 - Aired 12/2/2008

The team takes on the case of a fitness guru on an all-natural diet who collapsed while filming a video. Meanwhile, Foreman conducts Huntington's Disease drug trials and Thirteen signs on as a subject, Cuddy is forced to move into House's office, and Kutner uses House's name to run an online medical-advice website.

Directors: Deran Sarafian
Watch Now:AmazonApple TV
House Divided
star
7.76
3637 votes

#8 - House Divided

Season 5 - Episode 22 - Aired 4/27/2009

The team takes on the case of a deaf 14-year-old named Seth who collapsed after he started “hearing” explosions while competing in a wrestling match. When the team tries to test him for seizures, Seth loses vision in one eye, complicating House’s bunk theory of “Exploding Head Syndrome.” As his condition worsens, the team has an ethical disagreement about the patient and his mother’s adamant decision to forego cochlear implants to supplement his hearing. When the prospect of giving Seth the ability to hear for the first time in his life arises, House and the team are faced with a resounding decision. Meanwhile, House’s lack of sleep starts to play tricks on his mind, but he finds his insomnia may be a gift instead of a burden

Directors: Greg Yaitanes
Watch Now:AmazonApple TV
The Softer Side
star
7.72
3336 votes

#9 - The Softer Side

Season 5 - Episode 16 - Aired 2/23/2009

A patient with both male and female DNA has the team stumped. Meanwhile, House starts acting nicely, raising Cuddy's and Wilson's suspicions that something is terribly wrong.

Directors: Deran Sarafian
Writer: Liz Friedman
Watch Now:AmazonApple TV
Joy to the World
star
7.72
3283 votes

#10 - Joy to the World

Season 5 - Episode 11 - Aired 12/9/2008

House and his team deal with a bullied girl who collapses during her school's Christmas program. Meanwhile, Foreman and Thirteen grow closer during the Huntington's disease drug trials, House gives a patient a gift, the staff wonder who gave House a special gift, and Cuddy gets an unexpected gift.

Directors: David Straiton
Writer: Peter Blake
Watch Now:AmazonApple TV
Dying Changes Everything
star
7.72
3536 votes

#11 - Dying Changes Everything

Season 5 - Episode 1 - Aired 9/16/2008

In the aftermath of personal tragedy, Wilson resigns from the hospital... and from his friendship with House. Meanwhile, Thirteen struggles with her personal medical problems while helping treat an executive assistant with a similar situation to her own.

Directors: Deran Sarafian
Writer: Eli Attie
Watch Now:AmazonApple TV
Painless
star
7.71
3103 votes

#12 - Painless

Season 5 - Episode 12 - Aired 1/19/2009

House and the team try to diagnose a man living with severe, chronic pain; Thirteen and Foreman explore their complicated relationship; Cuddy discovers that caring for her baby leaves her with little time to run the hospital.

Directors: Andrew Bernstein
Watch Now:AmazonApple TV
Saviors
star
7.71
3294 votes

#13 - Saviors

Season 5 - Episode 21 - Aired 4/13/2009

Cameron postpones her vacation with Chase in order to ask House to accept the case of an environmental radical who collapsed at a protest with unexplainable symptoms. Although suspicious of her motives, House agrees. Since she pushed him to take the case so emphatically, House forces Cameron to take the lead and run many of the tests on the patient. Meanwhile, House is unsure of Wilson’s new healthy diet.

Directors: Matthew Penn
Watch Now:AmazonApple TV
Lucky Thirteen
star
7.71
3306 votes

#14 - Lucky Thirteen

Season 5 - Episode 5 - Aired 10/21/2008

Thirteen brings her one-night stand to the hospital after the woman has a seizure. However, the woman admits she slept with Thirteen just so she could get to House and have him diagnose her condition. Meanwhile, House continues to pay Lucas to spy on Wilson.

Directors: Greg Yaitanes
Watch Now:AmazonApple TV
Birthmarks
star
7.69
3183 votes

#15 - Birthmarks

Season 5 - Episode 4 - Aired 10/14/2008

While en route to his father's funeral, House must help the team with a differential diagnosis on a young Chinese girl who has collapsed under mysterious circumstances.

Directors: David Platt
Watch Now:AmazonApple TV
The Itch
star
7.68
3312 votes

#16 - The Itch

Season 5 - Episode 7 - Aired 11/11/2008

The team must treat an agoraphobic who refuses to leave his house, and have to work around Cuddy, who is less than thrilled at having hospital equipment relocated. Meanwhile, House is plagued by an itch, and Cameron and Chase have relationship issues.

Directors: Greg Yaitanes
Writer: Peter Blake
Watch Now:Apple TV
Unfaithful
star
7.62
3172 votes

#17 - Unfaithful

Season 5 - Episode 15 - Aired 2/16/2009

When a priest who runs a homeless shelter sees a bleeding Jesus hovering at his doorstep, he is admitted to the ER. House takes on the case as a distraction for the team while he confronts Foreman and Thirteen about their relationship. The team soon learns the priest had been involved in a molestation scandal that caused him to lose his faith. However, just as they are about to dismiss his case, the patient’s condition takes a drastic turn for the worse, and House grapples with his past and his belief

Directors: Greg Yaitanes
Watch Now:Apple TV
Not Cancer
star
7.62
3142 votes

#18 - Not Cancer

Season 5 - Episode 2 - Aired 9/23/2008

The team deals with an organ donor whose organs prove fatal, and the two surviving patients. Meanwhile, House hires a private detective to spy on Wilson, but hears a few things about himself that he'd rather not.

Directors: David Straiton
Watch Now:Apple TV
Here Kitty
star
7.61
3127 votes

#19 - Here Kitty

Season 5 - Episode 18 - Aired 3/16/2009

Morgan works in a nursing home with a pet cat who only sleeps next to people if they are about to die - and does so with alarmingly accuracy. When it seems the cat has predicted her own death, Morgan, convinced she is about to die, fakes a seizure in order to get to House to have him diagnose her before it’s too late.

Writer: Peter Blake
Watch Now:Apple TV
The Greater Good
star
7.61
2992 votes

#20 - The Greater Good

Season 5 - Episode 14 - Aired 2/2/2009

House and the team take on the case of a woman who collapsed in the middle of a cooking class, and they soon learn she is a highly-renowned cancer researcher who recently gave up her entire career in order to pursue her own personal happiness. Though the team struggles to understand how the woman could give up saving lives for the sake of her own contentment, each grapple with the pursuit of happiness (or lack thereof) in their own lives. As the patient’s condition continues to worsen, so does Thirteen’s as she begins to suffer serious and life-threatening reactions to the experimental Huntington’s Disease clinical trial. Meanwhile, Cuddy attempts to make House’s life miserable for him in retaliation for his part in her own unhappiness.

Writer: Sara Hess
Watch Now:Apple TV
Big Baby
star
7.60
3054 votes

#21 - Big Baby

Season 5 - Episode 13 - Aired 1/26/2009

Cuddy decides to spend more time at home to take care of her newly adopted baby and passes some of her day-to-day responsibilities off to Cameron, including supervising House. Cameron is forced to play House’s games and becomes involved in a power struggle as he and the team take on the case of a Special Education teacher who collapsed after spitting up blood in the middle of class. As House tests Cameron’s tolerance for his extreme measures, the patient continues to fall ill and House insists the teacher’s seemingly inherent goodness is actually a pathology.

Directors: Deran Sarafian
Watch Now:Apple TV
Joy
star
7.56
3288 votes

#22 - Joy

Season 5 - Episode 6 - Aired 10/28/2008

An ailing man suffers from blackouts and sleepwalks, leading the team to wonder if his sleepwalking is a symptom, or how the man is becoming exposed to something else. When the man's daughter grows ill as well, the team must provide a diagnosis before both die. Meanwhile, Cuddy adopts a newborn but when the birth mother displays a rash, she has to make a decision between putting the mother or daughter at risk.

Directors: Deran Sarafian
Watch Now:Apple TV
Emancipation
star
7.46
3076 votes

#23 - Emancipation

Season 5 - Episode 8 - Aired 11/18/2008

While Foreman takes on a pediatric case on his own, the rest of the team deals with a 16-year-old factory manager and emancipated minor who collapses at work. When Foreman's patient takes a turn for the worse, he's forced to question whether he can deal with the situation on his own, or if he needs House's help.

Directors: James Hayman
Watch Now:Apple TV
Adverse Events
star
7.46
3144 votes

#24 - Adverse Events

Season 5 - Episode 3 - Aired 9/30/2008

A painter's undiagnosed illness affects his work, and House and his team must look at the man's paintings to determine what's wrong with him.

Directors: Andrew Bernstein
Watch Now:Apple TV