The WORST seasons of A.P. Bio
Every season of A.P. Bio ever, ranked from worst to best by thousands of votes from fans of the show. The worst seasons of A.P. Bio!
When Harvard philosophy professor Jack Griffin fails to get his dream job and reluctantly moves back to Ohio to work as a high school Advanced Placement Biology teacher, he makes one thing very clear: he will not be teaching one bit of biology. Instead, realizing he has a room full of honor roll students at his disposal, Jack recruits the kids to help him mentally break his job-stealing nemesis and win back the position that's rightfully his.

#1 - Season 4
First Aired 9/2/2021
Season 4 of A.P. Bio continues the show's evolution into a high-energy, absurdist ensemble comedy. Released on Peacock, it focuses on Jack Griffin finally embracing his role as a chaotic mentor to his students while navigating his own unresolved family trauma.

#2 - Season 3
First Aired 9/3/2020
Season 3 of A.P. Bio marked the show’s transition from NBC to the streaming platform Peacock. This shift allowed the series to become more experimental, lean into its absurdist comedy, and focus less on Jack Griffin's (Glenn Howerton) desire to leave Toledo and more on his bizarre integration into Whitlock High.

#3 - Season 1
First Aired 2/1/2018
When Harvard philosophy scholar Jack Griffin finds himself teaching high school in Toledo, Ohio, he tosses the syllabus and recruits his students to help enact revenge on his rival.

#4 - Season 2
First Aired 3/7/2019
Having botched his chance to get out of Toledo last season, disgraced Harvard philosophy scholar Jack Griffin is once again stuck teaching biology class at Whitlock High for the lovable Principal Durbin.