Teresa Mendoza is a woman who is forced to run and seek refuge in America after her drug-dealing boyfriend is unexpectedly murdered in Mexico. In the process, she teams up with an unlikely figure from her past to bring down the leader of the very drug trafficking ring that has her on the run.
Teresa has to prove her worth to Camila. Meanwhile, Epifanio gets closer in his hunt for Teresa. Back in Mexico, Brenda desperately tries to find Teresa and hide from the cartel.
Teresa and Brenda risk everything in a game of extortion. Camila takes further steps to overtake Epifanio’s empire.
Camila, riddled with debt and short on supply, grows desperate and ponders giving Teresa up. Meanwhile, Brenda's burgeoning drug enterprise creates a rift between her and Tony.
The Mexican drug cartel comes after Teresa, forcing her on the run.
Teresa and crew rig a high-stakes narco horse race, but old enemies — and old flames — threaten to tear everything apart.
Camila sends Teresa out on a life-threatening, multi- million dollar midnight mission. Pressured by a lack of supply, Brenda puts her crew in the line of fire.
Teresa races to save a witness in the recent heist. With renewed confidence, Camila assures her partners that she’s back in business and vows to be done with Epifanio once and for all.
Teresa's loyalties are tested when she is asked to assassinate a DEA mole.
Teresa witnesses a horrific event that forces her to advance her plans. Now, safely in Dallas, Brenda needs money to survive, and starts assembling a rag tag team to help her sell drugs.
Aligning with the Jimenez Cartel, Camila’s operation goes underground. Teresa and Brenda try to start a new life utilizing knowledge from Güero’s book.
Camila sends Teresa out on a major drug operation to test her loyalty. In secret, Camila makes her first big move to take over Epifanio’s cartel. Meanwhile, Brenda plots her escape to America.
Camila sends Teresa and her crew to Chicago to secure a meeting with an elusive drug distributor.
Teresa flees Europe and starts fresh in Phoenix, Ariz.; she must deal with a commission of cartel bosses and a corrupt local sheriff.
Rocked by a deeply personal tragedy, Teresa battles a dangerous sicario and a mutiny within her own ranks.
With their payment deadline looming, Teresa and Camila need to find a new distributor, but their plans become threatened.
Teresa expands her business and proves herself to a smuggler who offers her a business opportunity.
While trying to destroy Epifanio's drug smuggling tunnels, Teresa and James come face-to-face with a group of American border vigilantes.
A deadly mistake mars Teresa’s first solo drug run and she soon finds herself in peril. Meanwhile, Brenda and Tony make the risky escape to Dallas.
Camila returns to Mexico to protect her life, while James hunts Teresa down. Meanwhile Teresa finds herself in grave danger taking Maria through the tunnel to Mexico.
An uncharacteristic blunder forces Camila and Teresa to go on the run from hit men, but as they flee, their bond grows deeper.
An FBI informant threatens Teresa's growing empire while she deals with turmoil within her family.
Teresa brokers a deal with an eccentric smuggler, Camila struggles to rebuild her empire, and Epifanio takes on a new partner he may not be able to control.
Hiding from Camila in Malta, Teresa tries to launch a drug empire of her own by striking a deal with a dangerous money launderer.
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