An ex-CIA agent and a mysterious billionaire prevent violent crimes with the help of an all-seeing machine that can predict events before they happen.
Reese finds himself on a perilous personal journey when he takes on a homicide case Detective Carter was never able to close.
Reese and Finch try to protect a psychologist whose unorthodox methods for helping his patients find closure could cost him dearly. Meanwhile, flashbacks reveal Finch’s fragile state in the days following the bombing that killed his best friend, Nathan Ingram.
When the Machine arranges for Finch to sit on the jury of a murder trial, he begins to suspect that a fellow juror is set to rig the proceedings. Meanwhile, Reese begins to open up to the department’s therapist.
Reese infiltrates a gang to get closer to a former Marine that the machine tagged.
Reese and Finch must protect Harper, a street-smart grifter, when her plan to steal cash from a medical marijuana dispensary goes up in smoke.
Reese and Finch question the machine's reliability when it prompts the investigation of a teenager who was killed years earlier; Finch recalls the origin of the machine.
Reese’s cover could be blown when he realizes the latest POI has ties to his old CIA colleague, Kara Stanton.
The Machine sends Reese and Finch to a wedding to protect a pair of POIs before their nuptials. Also, Fusco becomes angry at being kept in the dark by the team and takes it upon himself to investigate a string of missing person reports.
Reese and Finch wonder if they should intervene when they learn that a mob enforcer's life is in danger; Finch turns to an unexpected source for help.
When the machine names a New York cabdriver as a person of interest, any of his passengers could be a part of the impending crime.
When Reese and Finch discover that their latest POI has connections to Cold War Soviet espionage circles, they quickly learn how covert ops were handled in a world before The Machine.
Reese and Finch must figure out whether a young prosecutor is a victim or a suspect.
Reese and Finch try to unravel a threat to a promising young doctor.
The Machine’s latest number sends Reese to the suburbs.
As Finch and Reese try to protect six people simultaneously, clues lead them to a coastal town; when a storm forces Finch and Reese to seek shelter in a police station with a group of locals, they realize a killer may be in their midst.
Reese tries to protect a software programmer with a mysterious second life, but it’s unclear which side of her life the threat is coming from. Meanwhile, Claire, a young hacker whom Finch tried to protect from Samaritan, reaches out to him for aid.
Reese and Finch are puzzled when the machine names a 6-month-old baby as the latest person of interest; Detective Carter questions her allegiances when Elias resurfaces.
The Machine leads Reese and Finch to Wall Street when a sharp young trader at a major investment bank becomes embroiled in a multi-million dollar financial scam.
Reese must protect a bounty hunter who refuses to let the potential threat to her life deter her from the relentless pursuit of her target. Also, Finch tries to set the plan he began in Shanghai in motion.
Reese's cover job as an NYPD detective becomes complicated when the young brother and sister he's protecting become targets of a gang investigation.
The team must figure out if a prominent lawyer orchestrated the murder of her husband or if she is being framed; Carter is spotted with Reese by her new partner.
The Machine identifies Darren, a teenager whose brother was just murdered, as the next POI. Meanwhile, Finch is growing concerned that the son of his former business partner is dangerously close to finding out about the Machine.
Finch and Reese head to Atlantic City to protect the latest person of interest, an elderly gambler; Carter tries to clear another detective's name.
Reese protects an NYPD analyst whose investigation into a software glitch has drawn the attention of Samaritan. Also, Reese and Fusco are threatened by an ally of Elias’s, who is looking to avenge his friend’s death.