The BEST episodes of My Next Guest Needs No Introduction With David Letterman

Every episode of My Next Guest Needs No Introduction With David Letterman ever, ranked from best to worst by thousands of votes from fans of the show. The best episodes of My Next Guest Needs No Introduction With David Letterman!

TV legend David Letterman teams up with fascinating global figures for in-depth interviews and curiosity-fueled excursions in this talk show.

Last Updated: 4/11/2024Network: NetflixStatus: Continuing
Barack Obama
446 votes

#1 - Barack Obama

Season 1 - Episode 1 - Aired 1/12/2018

Former President Barack Obama reflects on political tensions and his family's life after the White House, and Dave visits Selma with Rep. John Lewis.

Ellen DeGeneres
87 votes

#2 - Ellen DeGeneres

Season 2 - Episode 2 - Aired 5/31/2019

Ellen reflects on some of the toughest and most gratifying moments of her life, and she and Dave make mischief on the set of her talk show.

Directors: Michael Steed
Watch Now:Amazon
Dave Chappelle
91 votes

#3 - Dave Chappelle

Season 3 - Episode 3 - Aired 10/21/2020

In a rare interview near his farm in Ohio, comedy legend Dave Chappelle reflects on his unconventional career, his family and the power of community.

Watch Now:Amazon
Lewis Hamilton
82 votes

#4 - Lewis Hamilton

Season 2 - Episode 4 - Aired 5/31/2019

World champion Formula One driver Lewis Hamilton looks back on his scrappy beginnings and gives Dave the thrill of a lifetime on the racetrack.

Directors: Michael Steed
Howard Stern
142 votes

#5 - Howard Stern

Season 1 - Episode 6 - Aired 5/31/2018

Howard Stern shares the stories behind his outsized radio persona, a heartfelt apology he issued to Dave, and his famous interviews with Donald Trump.

Watch Now:Amazon
Tina Fey
141 votes

#6 - Tina Fey

Season 1 - Episode 5 - Aired 5/4/2018

Tina Fey opens up about her family, the changing culture at "SNL" and the one moment she wishes she could take back. Plus, blues icon Buddy Guy

176 votes

#7 - JAY-Z

Season 1 - Episode 4 - Aired 4/6/2018

From paper routes to fatherly angst: Dave sits down with hip-hop icon JAY-Z and discovers they have more in common than he knew.

George Clooney
279 votes

#8 - George Clooney

Season 1 - Episode 2 - Aired 2/9/2018

George Clooney opens up about his humanitarian work, courting wife Amal and his failed baseball dreams. Plus, Dave visits George's folks in Kentucky.

Watch Now:Amazon
Malala Yousafzai
158 votes

#9 - Malala Yousafzai

Season 1 - Episode 3 - Aired 3/9/2018

From a Taliban attack to a Nobel Prize to Oxford: Malala Yousafzai walks Dave through her extraordinary journey, her life's mission and her new home.

Julia Louis-Dreyfus
50 votes

#10 - Julia Louis-Dreyfus

Season 4 - Episode 6 - Aired 5/20/2022

Julia Louis-Dreyfus takes Dave fishing and talks growing up with two families, serving Gumby tea on "SNL" and reality overtaking fiction with "Veep."

Billie Eilish
55 votes

#11 - Billie Eilish

Season 4 - Episode 1 - Aired 5/20/2022

Dave visits Billie Eilish to discuss inspiration, influences and imposter syndrome — and even manages to work in a little go-karting and Auto-tuning.

Melinda Gates
78 votes

#12 - Melinda Gates

Season 2 - Episode 5 - Aired 5/31/2019

Melinda Gates breaks down big global challenges and explains why it's vital to get more women in tech. Dave makes sandwiches with her husband, Bill.

Directors: Michael Steed
Ryan Reynolds
59 votes

#13 - Ryan Reynolds

Season 4 - Episode 4 - Aired 5/20/2022

Ryan Reynolds makes pizza for Dave while he discusses his youth in Canada, early days as an actor, life as a father and love of Welsh football.

Watch Now:Amazon
Tiffany Haddish
77 votes

#14 - Tiffany Haddish

Season 2 - Episode 3 - Aired 5/31/2019

Tiffany Haddish lights up the stage as she talks Dave through her journey from foster care to the bar mitzvah party circuit to big-time movie roles.

Directors: Michael Steed
Watch Now:Amazon
Robert Downey Jr.
80 votes

#15 - Robert Downey Jr.

Season 3 - Episode 2 - Aired 10/21/2020

The "Iron Man" star opens up about his showbiz childhood, addictions and comeback, then introduces Dave to the animal menagerie at his Malibu home.

58 votes

#16 - Lizzo

Season 3 - Episode 4 - Aired 10/21/2020

Music superstar Lizzo invites Dave to lay down a track at her home studio as they chat about flutes, protests, her time working with Prince and more.

Kanye West
93 votes

#17 - Kanye West

Season 2 - Episode 1 - Aired 5/31/2019

Kanye opens up about family, bipolar disorder, his Sunday Service gatherings and the backlash over his support for Trump. Dave scores new Yeezy gear.

Directors: Michael Steed
Kim Kardashian West
60 votes

#18 - Kim Kardashian West

Season 3 - Episode 1 - Aired 10/21/2020

Kim Kardashian West walks Dave through key moments from her life, including the O.J. trial, a Paris robbery, her law studies and a White House visit.

Kevin Durant
45 votes

#19 - Kevin Durant

Season 4 - Episode 5 - Aired 5/20/2022

Dave and Kevin Durant go one-on-one in basketball, shuffleboard and conversation as they cover family, focus, trash-talking, social media and more.

Will Smith
52 votes

#20 - Will Smith

Season 4 - Episode 2 - Aired 5/20/2022

Will Smith recalls his rap origins, the lasting impact of his parents, spiritual explorations, and one very fateful night at Quincy Jones' house.

Watch Now:Amazon
Cardi B
53 votes

#21 - Cardi B

Season 4 - Episode 3 - Aired 5/20/2022

Cardi B and Dave split a chopped cheese in a Bronx bodega and chat hooky parties, hip-hop, parenting, political science and protesting injustice.