The BEST episodes of Hamilton's Pharmacopeia season 3

Every episode of Hamilton's Pharmacopeia season 3, ranked from best to worst by thousands of votes from fans of the show. The best episodes of Hamilton's Pharmacopeia season 3!

Hamilton is fascinated by drugs. Join him on an inedible journey as he investigates the history, chemistry, and social impact of the world's most extraordinary mind-altering substances.

Last Updated: 3/9/2025Network: VICE TV (US)Status: Ended

8.36

22 votes

#1 - Synthetic Toad Venom Machine

Season 3 - Episode 1 - Aired 1/4/2021

Haunted by past mistakes, Hamilton embarks on a journey to correct an error in his reporting and identifies the origin of an international toad venom smoking phenomenon.

Watch Now:Amazon Apple TV

7.75

20 votes

#2 - Xenon: the Perfect Anesthetic?

Season 3 - Episode 3 - Aired 1/18/2021

Hamilton traces the multibillion year history of nitrous oxide on Earth and follows the strangest noble gas to the Czech Republic.

Watch Now:Amazon Apple TV

7.70

23 votes

#3 - Bufotenine: In Search of Hataj

Season 3 - Episode 5 - Aired 2/1/2021

Succumbing to viewer requests, Hamilton journeys to South America to understand the legend of Bufotenine, the world's oldest psychedelic.

Watch Now:Amazon Apple TV

7.68

25 votes

#4 - Ultra LSD

Season 3 - Episode 6 - Aired 2/8/2021

With the precise structure of LSD's molecular target identified, Hamilton discusses the new era of psychedelic research and meets pioneers of the field.

Watch Now:Amazon Apple TV

7.67

27 votes

#5 - A Positive Methamphetamine Story

Season 3 - Episode 2 - Aired 1/11/2021

From X-ray crystallography to vesicular dopamine release, Hamilton travels the country visiting meth labs to understand the process behind a great American folk art.

Watch Now:Amazon Apple TV

7.46

24 votes

#6 - Synthetic Ibogaine: Natural Tramadol

Season 3 - Episode 4 - Aired 1/25/2021

After revealing a scientific mystery around Tramadol-addicted cows in West Africa, Hamilton follows a Gabonese opiate addict to a psychedelic ritual.

Watch Now:Amazon