The BEST episodes of 20/20 season 49
Every episode of 20/20 season 49, ranked from best to worst by thousands of votes from fans of the show. The best episodes of 20/20 season 49!
20/20 brings you hard-hitting investigative reports, news-maker interviews and compelling human interest and feature stories.
#1 - Life on the Line
Season 49 - Episode 3 - Aired 10/10/2025
21-year-old mother Denise Amber Lee disappears from her North Port, Florida, home. Follow the real 911 calls as they unravel in this life-and-death case.
#2 - He's Right Behind You
Season 49 - Episode 1 - Aired 9/26/2025
A family is stalked, leading to the murder of a mom. Dramatic body camera video captures the unfolding investigation.
#3 - You Took My Daughter
Season 49 - Episode 7 - Aired 11/7/2025
At Fort Bragg, North Carolina, 24-year-old mother and Army maternity ward nurse Holly Wimunc suddenly vanished in July 2008. At her apartment, coworkers reportedly found smoke damage and signs of an intentionally set fire. While detectives scrambled to find her, her father, halfway across the country, was just learning his girl was gone.
#4 - Lost in the Night: Who Murdered Jessica Currin?
Season 49 - Episode 5 - Aired 10/24/2025
In Mayfield, Kentucky, 18-year-old single mother Jessica Currin was brutally murdered in 2000. The case haunted the town for years until a jury convicted Quincy Omar Cross in 2008. What began as a local tragedy has become a national conversation about truth, power, and accountability as Cross's claim of a wrong conviction gains momentum.
Watch Now:Apple TV#5 - What Happened to the McStays?
Season 49 - Episode 2 - Aired 10/3/2025
In 2010, Joseph and Summer McStay and their two young sons vanished from their Fallbrook, California, home. For nearly four years, the family’s fate remained unknown—until a grim discovery in the Mojave Desert turned the missing persons case into a homicide investigation.
#6 - Driven to Death
Season 49 - Episode 4 - Aired 10/17/2025
In Horry County, South Carolina, Gregory Rice's disappearance in early October 2020 sparked a search that eventually uncovered a secret affair.
#7 - The Murdaugh Family Murders
Season 49 - Episode 6 - Aired 10/31/2025
The Murdaugh family once held deep roots in South Carolina’s Lowcountry, where generations served as top prosecutors and wielded influence across legal and political circles. But behind the prestige was a web of corruption, financial crimes, and ultimately, murder.