Eight-year-old Doremi Harukaze aspires to be a user of magic, as she believes it would solve all her problems and help her confess to a boy she liked. One afternoon, she comes upon a magic shop and correctly suspects that the shop owner is a witch. The shop owner becomes a Witch Frog, "greenling", as this happens to witches when their true identities are discovered. In order to retain her original form, the shop owner, Majo Rika, takes Doremi as her apprentice to turn her into a witch. Doremi must take nine witch exams at night to become an official witch; however, she must never let her own identity as a witch be found out or the same fate that befell Majo Rika will happen to her.
When Doremi, Hazuki, Aiko, and Onpu travel to the Witch World to visit Majo Rika, they inadvertently walk into the Queen's garden and encounter a baby born from a special rose. They are given their powers back and are asked to take care of the newborn for a year.
On the day of graduation, Doremi refuses to attend school in fear of losing her friends forever. So she locks her self up in the Maho-Dou. Hana threatens to use magic, and Doremi comes out just in time before she shows everyone. In the end, after graduation, the girls send off Hana-chan, Majo Rika and the fairies with Hana promising to become the Queen fast so the can see each other again. Hana turns back into a baby when she enters the witch world. Doremi calls out to her and Hana-Chan turns around and says, "Thank you." While the theme for the original Ojamajo Doremi is played they show Momo-Chan and her parents in the airport while she says "See you. You are my best friend. I love you.(In english)" Onpu is shown with her parents in front of their car. Aiko is shown with her parents getting on the train. Hazuki is shown with Pop and (Doremi's) parents is Doremi's house. In the witch world Hana and the other babies are shown laying on Pao. Momo is shown in America showing Beth pictures of the past year with Doremi, Hana, and the others. Onpu is shown signing autographs for her fans. Aiko is shown bring tayoyaki to her dad, mom and grandpa. Hazuki is shown in a store with her mom. Her mom picks out a dress and Hazuki says 'no' and shows her something she likes. Doremi is shown giving a love-letter to someone.
Doremi accidentally loses her tap at the Summer Festival.
A new girl named Aiko Senōō from Osaka transfers to Doremi's class and unintentionally upsets Doremi and Hazuki at first. Once Doremi gets to know her, she befriends her and tries to find ways to cheer her up on Parents' Day at school.
On a school trip, Kaori takes charge of taking pictures, but she goes overboard and produces some embarrassing photos of everyone.
Aiko and Onpu argue with each other after Aiko misunderstands the importance of the idol's feelings.
The kindergardeners are preparing for the athletic meet. During practice, it's revealed that Kimitaka has a few cooperation and balance problems.
Doremi Harukaze comes across a magic shop and calls out the owner, Majorika, for being a witch, turning the latter into a witch frog. Now, she must become a witch apprentice herself to return Majorika to her normal self.
After fixing up the magic shop and dubbing it Mahōdō, the girls await their first customers and are visited by a singing witch wholesaler Dela.
After Hana passes another health examination, Doremi, Hazuki, and Aiko go to see Onpu's filming in Kyoto. The kid who plays Onpu's brother, Chikara, gets jealous of Onpu spending more time with Doremi and the others.
Doremi and her best friend Hazuki Fujiwara want to swap lives for a day, as they both feel that the other is luckier. However, this leads to a few consequences.
Majorika loses her shop to Dela in a card game, and her arch-rival Majoruka takes over.
When returning the injured Kanae Īda to her father's steak shop, Doremi and the others discover the pall of bad luck covering the place and set out to uncover the mystery. They are appointed as Pureleine by the Queen to capture Bad Cards, as they have hearts pure enough to be able to do so.