The BEST episodes of The Hot Zone

Every episode of The Hot Zone ever, ranked from best to worst by thousands of votes from fans of the show. The best episodes of The Hot Zone!

The frightening spread of the Ebolavirus (season 1) and anthrax (season 2).

Last Updated: 3/3/2024Network: National GeographicStatus: Ended
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Hidden
star
7.83
749 votes

#1 - Hidden

Season 1 - Episode 6 - Aired 5/29/2019

A volatile situation inside the research facility comes to a head; Dr. Jaax steps up, but exhaustion threatens the precision needed to sterilize the threat; the press arrives, and neighbors become aware of the danger next door.

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Quarantine
star
7.72
755 votes

#2 - Quarantine

Season 1 - Episode 5 - Aired 5/29/2019

Dr. Nancy Jaax works tirelessly to find out why the virus is behaving differently than expected in human victims; unforeseen dangers arise at the research facility; Jaax is forced to make a choice between her family and her duty to her country.

Directors: Nick Murphy
Watch Now:AmazonApple TV
Arrival
star
7.72
939 votes

#3 - Arrival

Season 1 - Episode 1 - Aired 5/27/2019

Dr. Nancy Jaax has one of the most dangerous jobs in the world handling deadly viruses; after a lab accident, she is faced with a possible Ebola outbreak on U.S. soil.

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Expendable
star
7.65
813 votes

#4 - Expendable

Season 1 - Episode 4 - Aired 5/28/2019

An employee at the monkey research facility falls ill, causing Dr. Nancy Jaax to fear the virus has spread to the human population; Jerry Jaax searches for a way to protect his wife; and Dr. Wade Carter is obsessed with exposing the dangers of Ebola.

Directors: Nick Murphy
Watch Now:AmazonApple TV
Charlie Foxtrot
star
7.63
841 votes

#5 - Charlie Foxtrot

Season 1 - Episode 3 - Aired 5/28/2019

Representatives from varying agencies disagree on how to handle Dr. Nancy Jaax's discovery, so she realizes there are few protocols in place for containing a deadly virus on the U.S. soil; and an employee at the monkey research facility falls ill.

Directors: Nick Murphy
Watch Now:AmazonApple TV
Cell H
star
7.62
889 votes

#6 - Cell H

Season 1 - Episode 2 - Aired 5/27/2019

Dr. Nancy Jaax and her lab partner, Dr. Peter Jahrling, must take matters into their own hands to determine the source of the virus before it spreads; Dr. Jaax convinces an employee to hand over samples from infected monkeys.

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RMR-1029
star
7.59
201 votes

#7 - RMR-1029

Season 2 - Episode 6 - Aired 11/30/2021

With two suspects in question, Ryker’s own beliefs about the case are tested. As pressure from the FBI rises, Bruce unravels.

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Stentor Roeselli
star
7.54
200 votes

#8 - Stentor Roeselli

Season 2 - Episode 5 - Aired 11/30/2021

All eyes shift to “Mr. Z.” As they start to zero in on a suspect, Ryker and Dani get new assignments - but that won’t stop them from chasing their lead.

Watch Now:Apple TV
Neither Rain nor Sleet…
star
7.54
216 votes

#9 - Neither Rain nor Sleet…

Season 2 - Episode 3 - Aired 11/29/2021

An attack on Capitol Hill sends Ryker and his team to a mail facility that’s become a hot spot for anthrax infections.

Directors: John Fawcett
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Dream Boldly, Live Fully
star
7.53
216 votes

#10 - Dream Boldly, Live Fully

Season 2 - Episode 4 - Aired 11/29/2021

The FBI learns more about Bruce Ivins’ peculiar past behaviors after an old colleague raises red flags. Ryker and Dani trace the origin of the letters

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Hell’s Chimney
star
7.40
223 votes

#11 - Hell’s Chimney

Season 2 - Episode 2 - Aired 11/28/2021

Ryker’s investigation moves to New York as another case of anthrax occurs. Bruce Ivins begins having suspicions of his coworkers.

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Noble Eagle
star
7.34
268 votes

#12 - Noble Eagle

Season 2 - Episode 1 - Aired 11/28/2021

In Florida, a man mysteriously falls ill and dies. Special Agent Matthew Ryker suspects an anthrax attack - how many others have been infected?

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