Two guys in their early 30s are human guinea pigs for a testing facility known as Testico. As they try to live their lives as normally as possible, they have to deal with the potential side effects of a new product, experimental medication, or treatment.
Peter becomes totally paralyzed by a potent new muscle relaxant, and must use Ron for his daily care.
After losing something unexpected, in the pants area, Peter and Ron test the waters to see what it's like to be a woman.
When the doctors at Testico tell Ron and Peter they've lost the ability to feel pain, they turn into daredevils.
A radical new pill has Peter believing he has a miracle growing inside him.
Ron and Peter begin imagining symptoms after Testico will not tell them what they are testing out.
As the guys face death, they come to the realization that they have yet to really live.
Nugget moves into Ron and Peter's apartment, to live rent free, after they are blinded by a new shampoo.
Ron and Peter must refrain from sex for a week when they test chastity belts.
Ron and Peter test out a new truth serum for Testico, which unravels Peter's past and puts his friendship with Ron in jeopardy.
For Ron and Peter, a brain washing experiment goes horribly wrong, but not for Nugget.
Ron and Peter test an experimental new pheromone spray that makes them irresistible to women.
Ron and Peter test the world's strongest glue and they become closer than they ever thought possible.
When super slob Peter earns the boys a chance to test a million dollar vacuum, they discover having a hyper intelligent, military grade home appliance really sucks.