The BEST Episodes of Ozzy & Drix

Every episode ever - ranked by fan votes!

Last Updated: Mar 3, 2021

Network: Cartoon Network

A year after Ozzy and Drix defeated Thrax and saved Frank from dying in Osmosis Jones, Ozzy and Drix chase a scarlet fever bacterium (possibly thanks to Frank resuming his poor eating habits). During the chase, Ozzy, Drix and the germ get sucked up from Frank by a mosquito and arrive on a Cuban American teenager named Hector Cruz. After some initial problems with their new home, both are installed as Private Investigators, vowing to protect Hector's well being from any viral threat, not to mention, help him through the changes in his teen years.

Where There's Smoke

#1 - Where There's Smoke

Season 1 - Episode 8 - Aired Nov 16, 2002

Ozzy must keep Nick O'Teen from getting to the brain where he will cause Hector to smoke.

star 8.50
2 votes
Street Up

#2 - Street Up

Season 1 - Episode 6 - Aired Oct 19, 2002

Drix tries to learn how to act ""street"" and ends up helping an acne germ create a huge zit on Hector's face.

star 8.33
3 votes
Sugar Shock

#3 - Sugar Shock

Season 1 - Episode 12 - Aired Feb 8, 2003

Hector binges on candy, creating a sugar rush that speeds up all the cells and causes the bacteria population to swell. When his parents cut him off sugar, his drop in blood sugar slows all the cells to a crawl. But the bacteria need sugar, so they form an army to raid Hector's sugar reserves. Now Ozzy and Drix, with the help of the Mole, must take on the bacterial army.

star 8.33
3 votes
Home with Hector

#4 - Home with Hector

Season 1 - Episode 1 - Aired Sep 14, 2002

By way of a simple mosquito bite, Ozzy and Drix are transferred into the body of a 13-year-old boy, Hector. Unfortunately, a nasty germ named Scarlet Fever is also transferred, and our heroes have to capture him before he wreaks havoc on the City of Hector.

star 8.17
6 votes
An Out of Body Experience (2)

#5 - An Out of Body Experience (2)

Season 2 - Episode 2 - Aired Aug 30, 2003

Ozzy is still in Christine, using REM sleep (or Random Eye Movement). He calls Drix for help, thats when he learns he's gender morphing. When a cell from a certain gender goes to a body of another gender, that cell becomes that gender. With Drix's plan, and the help of another Drixinol cold pill in Christine called ""Drixina."" Ozzy might come back to Hector, and keep Christine from having pneumonia.

star 8.00
2 votes
Puberty Alert

#6 - Puberty Alert

Season 2 - Episode 5 - Aired Sep 20, 2003

Hector discovers hair growing on his chin; testosterone gang ties up the mayor and wreaks havoc.

star 8.00
2 votes
A Cold Day in Hector

#7 - A Cold Day in Hector

Season 2 - Episode 9 - Aired Oct 25, 2003

While snowboarding with Travis, Hector crosses an off limits area. Hector starts to freeride, but falls and makes a rip in his trousers. This causes a virus named Cryle to drop Hector's temperature. Ozzy and Drix get ready for a day at the beach, but have to stop Cryle from making Hecotr die of hypothermia.

star 8.00
2 votes

#8 - Strep-Finger

Season 1 - Episode 3 - Aired Sep 28, 2002

Ozzy becomes jealous of a super agent (Penicillin G) who has been injected into Hector to track down a powerful germ known as Strepfinger.

star 7.60
5 votes
Oh My Dog

#9 - Oh My Dog

Season 1 - Episode 5 - Aired Oct 12, 2002

Drix's new pet dog, Dander, is mistaken for a Allergen that is threatening the city.

star 7.50
4 votes
An Out of Body Experience (1)

#10 - An Out of Body Experience (1)

Season 2 - Episode 1 - Aired Aug 23, 2003

Ozzy gets transfered into a girl named Christine's body when she gives Hector mouth-to-mouth when he jumps off the high dive to impress her, while there Ozzy starts changing colors and acting like a girl also he is arrested because they think he is a virus.

star 7.50
2 votes
Aunti Histamine

#11 - Aunti Histamine

Season 2 - Episode 7 - Aired Oct 4, 2003

Hector uses a Nose spray to clear his nose, and Drix's Aunt appears. Suddenly, there's a drop in water in Hector and Ozzy thinks Drix's aunt is causing it.

star 7.50
2 votes
Double Dose (aka Ozzy and Ozzy)

#12 - Double Dose (aka Ozzy and Ozzy)

Season 2 - Episode 11 - Aired Jun 21, 2004

Ozzy goes into mitosis and a four armed evil clone doubles from him trying to steal the iodine.

star 7.50
2 votes
Cavities (aka Journey to the Center of the Tooth)

#13 - Cavities (aka Journey to the Center of the Tooth)

Season 2 - Episode 13 - Aired Jul 5, 2004

Hector eats too much sugar and doesn't brush so he gets a cavity caused by General Malay.

star 7.50
2 votes
A Lousy Haircut

#14 - A Lousy Haircut

Season 1 - Episode 4 - Aired Oct 5, 2002

When Ozzy discovers there are lice eggs in Hector's hair, he and Drix venture onto the scalp to knock the eggs off, only to end up running into the monstrous Mother Louse!

star 7.20
5 votes

#15 - Reflex

Season 1 - Episode 2 - Aired Sep 21, 2002

Ozzy accidentally produces a neural spasm that causes Hector to kick the school bully. When the bully threatens to beat up Hector after school, Ozzy has to figure out a way to help Hector defend himself.

star 7.00
4 votes
Gas of Doom

#16 - Gas of Doom

Season 1 - Episode 7 - Aired Nov 9, 2002

Ozzy, Drix and Maria commandeer a submersible police craft into the intestines to stop a gas build-up that threatens Hector's social situation.

star 7.00
2 votes
The Conqueror Worm

#17 - The Conqueror Worm

Season 2 - Episode 4 - Aired Sep 13, 2003

Hector eats a sausage that he barely cooked and gets sick which leads him to getting two worms in his the male worm dies after mating, but the female survives, so Ozzy tries to kill it along with a crazy captain and Drix.

star 7.00
2 votes
Ozzy Jr.

#18 - Ozzy Jr.

Season 1 - Episode 10 - Aired Dec 7, 2002

Ozzy thinks he's going to have a baby, but it turns out he's been infected with an intracellular bacteria by returning villain Strepfinger. Ozzy and Drix must find a way to destroy the parasite growing within Ozzy before it spreads its infection to all of Hector.

star 6.67
3 votes
The Globfather

#19 - The Globfather

Season 1 - Episode 9 - Aired Nov 30, 2002

When Sal Monella, a poisonous gangster germ, kidnaps the Mayor with plans to poison Hector, Ozzy and Drix must come to his rescue.

star 6.50
2 votes
Lights Out!

#20 - Lights Out!

Season 2 - Episode 3 - Aired Sep 6, 2003

Everyone inside Hector forgets who Ozzy and Drix are when Hector experiences a concussion, forcing them to locate the site of the concussion, so they can reboot Hector's memories.

star 6.50
2 votes
Tricky Ricardo

#21 - Tricky Ricardo

Season 2 - Episode 6 - Aired Sep 27, 2003

After getting injured on a police case, Maria is sent home to rest for the week. She decided to use this time to work on a family reunion coming up for her. Drix notices a rip on the corner of Maria's family picture. Maria doesn't seem to want to talk about it but then Ricky comes in and starts putting the puzzle pieces together. Maria and Ricky share their past with Drix which turns out as Ricky being the family prankster. Maria lost his trust in him so Drix decides to help Ricky get it back. He allows him to be a private eye along with Ozzy with not so good results.

star 6.50
2 votes
A Growing Cell

#22 - A Growing Cell

Season 2 - Episode 8 - Aired Oct 11, 2003

Hector is super-sizing at fast-food resturaunts far too much, which gives Sticity, a bad cholestrial beatnik, the chance to kidnap a fat cell family's child, in an atempt to clog an artery. Can Ozzy and Drix (and the new navigational system, installed by Drix, named Backseat) return the huge blob to his parents in time?

star 6.50
2 votes

#23 - Growth

Season 1 - Episode 11 - Aired Feb 1, 2003

The Mayoral election is coming up, and Spryman's opponent, a nerdy brain cell named Sylvian Fisher, is using a secret growth formula to cause destructive growth spurts and make the Mayor look bad. Ozzy and Drix must stop this fiendish plan, which becomes more difficult when Sylvian takes the growth formula himself and becomes a raging, muscular monster.

star 6.00
2 votes
The Dream Factory

#24 - The Dream Factory

Season 1 - Episode 13 - Aired Mar 1, 2003

Hector's terrible recurring nightmare is keeping everyone in the City of Hector awake. Ozzy and Drix go to the ""Subconscious Network,"" where dreams are produced, and enter Hector's nightmare to help him face his fear.

star 6.00
2 votes
Supplements (aka Triumph of the Supplements)

#25 - Supplements (aka Triumph of the Supplements)

Season 2 - Episode 10 - Aired Jun 14, 2004

When Hector accidently breathes in lead, the lead gang cause him to make him feel ill. The Mayor then makes Hector eat cereal so he can bring in The Supplements.

star 6.00
3 votes