Early 1960s sitcom about an architect named Wilbur Post and his talking horse, Mister Ed.
After Ed saves the life of a small girl in the park, a greatful Grandfather invites Ed and the Posts to his estate in Catalina and Ed doesn't want to go.
Carol wants an antique statue and Wilbur won't let her buy one. She then tells him that she will go on a fish diet if she can't get the statue. She then buys it anyway and Wilbur finds it and takes it back. Finally Wilbur changes his mind and buys it for her anyway. She then takes it back. Then everyone it comes in contact to takes it back and when Wilbur comes to buy it for the last time, the store owner is bout to go crazy.
Ed gets angry at Carol and thinks she is mistreating him because she has Ed hitched to a surrey when Wilbur refuses to buy her a new car.
Ed protests when Wilbur and Carol go to Pine Lake Lodge for vacation. Despite his protests, they leave him behind this time anyway.
A Granfather is eternally greatful when Ed saves his grandaughter's life at the park. The Grandfather invites the Posts and Ed to his palatial state in Catalina, but Ed refuses to go with.
Ed reads in the paper about a cat who is willed a great deal of money, and Ed wants to know if he is in Wilbur's will.
Wilbur tries to have a petition eliminating horses from the neigborhood recalled after Carol unwittingly signs a petition to get rid of them.
Ed has adopted a wild goat and decides to give it to Wilbur as a birthday present.
Ed falls madly in love with a French female horse, but is turned off a little when he realizes that she is taller than him.
Ed writes to Dear Abby on account of getting a bachelor stall.
Kirkwood starts taking up horseback riding and his new horse is really fast, so he challenges Wilbur and Ed in a race.
Wilbur accidentally ends up pulling the stuffing out of a toy horse. When Ed overhears Wilbur talking about "Stuffing the horse", Ed goes into shock.
Ed decides to get contact lenses when he is spotted in public wearing glasses.
A collection of items are gathered for an auction and are stored in Ed's barn. The collection of objects reveal a fierce looking creature.....a dragon horse.
Ed wants a heater for the barn and Carol needs a new refrigerator. What is Wilbur going to decide to do?
Ed accidentally becomes the "drop" for stolen money, taken from a bank where Wilbur was making a deposit.
When Wilbur designs a post office with a Pony Express statue, Ed becomes amazed at the thought that his ancestors used to deliver mail.
Carol offers to look after a friends cat, but Wilbur ends up doing most of the work, making him busy. Ed then starts then feeling neglected.
A new boy enters the neigborhood and none of the kids like him. To try and get the kid together with the other kids, Carol throws a party. Ed then hatches a scheme to show that the boy is brave by riding the "Mean" Ed.
Ed toutors Wilbur on everything from reference books to foreign languages to win a contest that awards $5,000.00.
Wilbur takes in a magician's elephant in the barn and Jumbo drives Ed crazy with his antics.
Ed diets to impress a filly, while at the same time, Wilbur's father-in-law decides to drop by and visit.
Ed manipulates Wilbur to try and get him to play chess with him, but Wilbur doesn't believe him when Ed tells him that there is a burglar loose in the house.
Wilbur thinks that Ed looks ungroomed and needs a good haircut, so he gets a hairdresser to do the job.
Wilbur has promised to take Ed camping, but the visit of Addison's mother spoils that from happening.