Masters of Sex

The BEST seasons of Masters of Sex

Every season of Masters of Sex ever, ranked from best to worst by thousands of votes from fans of the show. The best seasons of Masters of Sex!

The series chronicles the unusual lives, romance and pop culture trajectory of William Masters and Virginia Johnson. Their research touched off the sexual revolution and took them from a mid-western teaching hospital in St. Louis to the cover of Time magazine.

Last Updated: 6/19/2022Network: Showtime
Season 1
223 votes

#1 - Season 1

First Aired 9/30/2013

In 1956, former nightclub singer and single mother Virginia Johnson becomes the assistant to renowned OBGYN William Masters. They embark on their pioneering study in human sexuality while trying to navigate their personal feelings for each other. Masters' wife Libby tries to conceive a child to save her marriage. Dr. Ethan Haas chafes under the supervision of Dr. Masters and deals with a changing society. University Provost Barton Scully struggles to support his protege William Masters while dealing with a long-held personal secret.

Season 2
154 votes

#2 - Season 2

First Aired 7/14/2014

Dr. William Masters and Virginia Johnson struggle to get their work back on track while taking their relationship to a much more intimate place. Libby flounders in a loveless marriage and turns to volunteering. Former prostitute Betty DiMello tries for the American dream and ends up working with Masters and Johnson. Dr. Austin Langham becomes the spokesman for a popular diet company and the boy toy to its aggressive founder.

Season 4
60 votes

#3 - Season 4

First Aired 9/12/2016

The seventies are in full swing and sexual experimentation is all the rage. Masters and Johnson should be celebrating, but their clinic is in legal trouble, their personal lives are in tatters and their relationship is on the rocks.

Season 3
102 votes

#4 - Season 3

First Aired 7/13/2015

Welcome to the swinging sixties. Thrust into the spotlight by the publication of their controversial study, Dr. William Masters and Virginia Johnson find themselves the unlikely leaders of the sexual revolution. But as newfound fame and pressures mount, their relationship becomes twisted and tangled – putting the couple in a position that even they might not be able to handle.