Animated Louie lived at home with his father, Andy (a grumpy war veteran), mother, Ora, and little brother, Tommy.He also has other brothers and sisters,but they don't appear every time. Each episode began with a live-action appearance of Louie Anderson introducing the show and setting up the plot. The show focused mostly on the funny events of life growing up.
Earl Grunewald is promoted to be a main worker of the tractor factory. While the Grunewald family goes for a ski trip, Louie pretends to be a ski master, so the Anderson family also joins.
A tornado attacks the Cedar Knoll and Louie gets afraid of the tornado, so he stays in his room and doesn't want to leave until the cow, which was trapped on a tree because of the tornado, confronts him.
Louie's class must give a speech and if someone wins, the class will go to Washington. Louie buys a speech from Glen Glenn and he wins. Andy accompanies the trip because he was in a war with the president. After Andy tells Louie he must always tell the truth, Louie tells the truth about the speech.
Aura gets a call from the doctor, telling her she's going to have a baby. Louie thinks if the baby is born, someone will leave the family and he thinks it might be him. It is revealed in the end that the doctor made a mistake and she's not pregnant.
For his vacation science homework, Louie has to give a detailed report on honey bees. He ends up enlisting the help of his father on this project, but Andy ends up taking over the care and observation of the bees and develops a special kinship with the bees. Louie tries to figure out how he is going to give a presentation on the bees when he can't get anywhere near them with his father in the picture.
Little Louie's never met a job he didn't like, but he does (eventually) get his household tasks done. Yet, he may have taken on a task that's more than he can handle when he tries to help down-and-out friend of the family get back on his feet. It's a single act of kindness - but it's doubled his chores!
When little Louie discovers he has a real talent for the game of chess, he tries to hide his identity at the big all-school chess tourney by becoming The Masked Chess Boy. (But even a mask can't hide his enthusiasm for scarfing down donuts!) Share the fun as Louie inspires his pals to reach for their dreams without worrying what other kids say.
Mrs.Glenn must go to hospital,because she got sick,bit suddenly the neighbours start to act strangely.Even her son is nice to Louie.Then Louie finds out if everyone can hear her voice,they will be normal again.So they give a party,for Mrs.Glenn's operation.When she felt better,she was home again,and the neighbourhood is normal...again.Watch Now:Amazon
Louie meets famous comedian Kazoo.Kazoo came to town,to see his mother Ora.He wants Louie to come and watch his show with his mother.Well,Louie wants it,but his mother doesn't.After the show,Louie decides to become a comedian.So,he asks Kazoo to help him.Louie is very good,and he is even going to stand and laugh people on audition.But,when he finds out,that being comedain has some thing to do with insulting people.
For Louie's birthday, his grandma gives Louie a sweater which she made for him. While trying to write the thank you letter, Louie decides to instead play with his friends. When he finally writes the letter, he finds out his grandma has died.
It's election day.There are three candidates,Melvin,Toddler and Mike.Louie is Mike's campaign manager.But,he doesn't know what to do now.So he asks his his parents for help.While he is lookinf for help,Andy is bowling with his friends.He tells Louie that he isn't loser because Andersons often lose,he tells him that he's a winner.Mike's idea is that they mustn't eat lima beans for lunch in cafeteria,while Toodler's idea is that reces must be longer.Anyway,Melvin wins so neither Toodler gets anything,neither Mike.
Louie's teacher is sick,so new teacher arrives,Mrs.Robertson.She is very pretty and every boy falls in love with her.To get her for himself,Louie starts to read books like Romeo and Juliet.Now he knows everything about that and Mrs.Robertson starts to like him very much.But when Andy finds about that,he goes to the principal to tell her she must fire the new teacher.But he actually finds out that she also knows much about wars.So,he helps her.and she is now hired at the Military Academy.
While shopping, Louie ends up stealing candy, so he tries to get rid of it during Halloween.
The Anderson family decides to go to the Sniffer land.But it is very far.On their way,they were in danger,they had a lot of fun.They traveled by train,but it broke,then they travel by plane,by bus,by ballon...But the most exciting part was when Louie fell in the water and snake almost bite him!When they manage to Sniffer land,it was closed.But that doesn't matter,because Louie actually had the most exciting vacation of all kids in the town.Watch Now:Amazon
Louie and Mike create a spaceship which causes Andy to be declared ambassador of the Earth.
Louie must play the prince for the school performance about Sleeping Beauty. Meanwhile, Andy replaces his boss. Louie gets his first kiss.
It's time for family picture,so Anderson family decides so.They will take a family picture,well,the only problem is: Louie and Tommy don't want to participate,they don't want to take family picture.Watch Now:Amazon
Louie wants to have a dog much to Andy's chagrin. Louie takes a dog that has been trained to be a guide for the blind.
Louie feels he's good at basketball and Andy tries to be in support him. Aura decides to eat healthy food.
Ora gets very sick and no one can help her around the house because she always does the most hard jobs at home.So,Louie must help her around the house.But if he does that,he will have no time to get a present for his mother because it's Mother's day.Watch Now:Amazon
New kid comes to school,and his name is Sean.It appears Jeannie likes him very much.Louie doesn't like that so he wants to know how could he have Jeannie.So,he asks his mother and father for help.Mum tells him a story how did she met Andy,but Andy tells completely different version of the story.After that,Louie tries to play tuba in the school to impress Jeannie.The only problem is he plays awful.At the end,Louie hits Jeannie's window with the snowball,and Jeannie opens it.He plays the song in the middle of the night just to her.
When Ora and Andy leave to go and visit Ora's sick mother, Louie and Tommy are left home alone to fend for themselves during a blizzard.
Louie makes a deal with his Dad to get out of his much-hated gym class if he agrees to play little league baseball. Much to Louie's dismay and bad luck, his baseball coach ends up being his tyranical gym teacher. After the coach is hit in the head by Louie's bat during a game Louie's dad Andy steps in as the coach and whips the team into shape in true military fashion--literally. While Andy is teaching the team battle strategies, Louie's mom teaches them actually baseball tips and tricks on the side. Of course in the end, Louie's team ends up in the big championship game and the team's newfound skills are put to the test.