The BEST episodes of Cold Case: The Tylenol Murders

Every episode of Cold Case: The Tylenol Murders ever, ranked from best to worst by thousands of votes from fans of the show. The best episodes of Cold Case: The Tylenol Murders!

Who really laced Tylenol with cyanide? This true-crime series examines alarming theories behind the unsolved killings — and tracks down a key suspect.

Last Updated: 7/26/2025Network: NetflixStatus: Ended

7.33

79 votes

#1 - The Bitter Pill

Season 1 - Episode 2 - Aired 5/26/2025

A key suspect maintains his innocence, even as authorities discover his suspicious past and possible motive. Tylenol unveils new triple-seal packaging.

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7.14

73 votes

#2 - Sealed for Your Protection

Season 1 - Episode 3 - Aired 5/26/2025

Decades after the murders, a victim's daughter searches for justice — and uncovers forgotten evidence that supports a controversial theory.

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7.12

94 votes

#3 - Pain Killer

Season 1 - Episode 1 - Aired 5/26/2025

After cyanide-laced Tylenol kills multiple people across Chicago, police and the media scramble to spread a nationwide warning.

Watch Now:Amazon