Ippo the Japanese Featherweight champion will defend his title against amazing challengers. Takamura fights for the second WBC title in the middleweight class, and Aoki fights for the Lightweight title.
Takamura is knocked unconscious while standing yet again, and remembers all of the pain, suffering, and disrespect he faced for the sake of this match. Realizing that his pain is because of Bryan Hawk, he begins fighting back, this time driven purely by instinct and anger. Takamura turns the table, but the champion on the ropes has one last trick up his sleeve...
Ippo mounts a desperate, full frontal assault as Sawamura continues to toy with him. Determined to take back the pace, Ippo begins to dodge the Bullets and get into a rhythm as he strikes back. Almost naturally he falls into the Dempsey Roll pattern, and Sawamura makes his move!
The evolved Dempsey Roll saved Ippo from the jaws of defeat. Bolstered by the cheering fans, he chases down Sawamura. But with Sawamura more willing than ever to risk an illegal move, will Ippo's last bit of energy be enough to defend the title?
A flashback shows how Sendo joined his gym. Ippo gets knocked down two times but when he gets up the fifth round gets more brutal. The fifth round ends and after that, the sixth round begins and is just as brutal as the last round.
Date tries the heart-breaker shot but Martinez blocks it with his elbow breaking Date's hand. By the end of the round Date's hand, jaw, and ribs are broken. After ten rounds the match has a winner.
Takamura is outsped once more and knocked unconscious, but manages to recover just in time. Relying on what he has learned from the coach, he knocks down Hawk and discovers his weakness! An all-out brawl ensues and Takamura comes out on top! Takamura begins the next round with a KO proclamation - but can he really end the fight in this round?
Takamura takes the pace at the beginning of the match, but Hawk unveils his unique style that allows him to dodge and attack simultaneously! After being caught off-guard and taking a beating in the first round, Takamura uses his speedy footwork to circle around Hawk, but Hawk outspeeds him and knocks him down. Can Takamura learn to counter Hawk's wild fighting style in time?
Kamogawa resorts to pounding a log with his bare fists as he trains to face Anderson and avenge Nekota. Anderson rediscovers his pride as a boxer and brings Miguel along as his cornerman. Everything comes down to this!
Despite using all of his remaining energy, Takamura cannot break through Hawk's defense and is left with no way to fight back. Hawk's wild bloodlust comes out, and he aims to kill Takamura in the ring! With nothing supporting him but the love of his friends and the coach's help, can Takamura mount a comeback?
When Miyata confronts Ippo about their promise, it is revealed that Miyata has risen far above Ippo's level due to his over-reliance on the Dempsey Roll. When Ippo's next challenger, Shimabukuro Iwao, declares that he will destroy the Dempsey Roll, Ippo decides to train his Dempsey Roll so that it has no weaknesses. The coach decides to help Ippo, even if it means fighting against modern boxing itself!
Imae’s long hours of research quickly pay off as he decimates Aoki by countering every one of his trademark attacks, even the Frog Punch! As Tomiko watches on and the crowd awaits the inevitable knockout, Aoki does something that leaves the whole arena in shock.
Ippo starts the third round by charging at Sendo but then hesitates which leads to Sendo beating Ippo all through the third round. The fourth round is a different story being more in the favor of Ippo.
Ippo reads Mari's article. Ippo invites Nekota to his fight. Both Sendo and Ippo have their weigh in. Sendo and Ippo begin their rematch with Ippo getting a very early knockdown on Sendo.
Takamura, Kimura, and Itagaki go to the beach because of their training camp while Aoki and Ippo go to the beach with Kumi and Tomiko, the two don't train because of they both had a match recently.
Sendo and Ippo's fight begins guns blazing with the two giving each other blow for blow. Ippo finds out that Sendo has the advantage of having a bigger frame.
The coach and Nagi see Hawk's devastating boxing firsthand. Takamura barely makes weight and is taunted by Hawk for his skinny appearance. Later, when a press conference turns into utter chaos, all of Japan roots for Takamura to beat Hawk. Ippo makes a risky promise to Takamura, but will he be able to fulfill it?
Both Takamura and Eagle are bleeding from their eyes, the doctor is about to stop the match but Takamura tells him to continue the match. Takamura can hardly see, one eye is swollen, the other is covered in blood.
Sawamura's blatant fouls and bullet-like left jabs leave Ippo scrambling to establish some kind of rhythm. He stubbornly forces his way inside, but is he charging headfirst into a trap?