The Best Episodes of Grey's Anatomy

Losing My Religion (2)

#1 - Losing My Religion (2) 8.63

Season 2 - Episode 27

This episode is the second part of a two-hour season finale. Richard tries to get information from Addison about a family member's condition. Callie and George have a talk about his feelings. Meredith and Derek have a talk about Doc.

Directors: Mark Tinker
Death and All His Friends

#2 - Death and All His Friends 8.62

Season 6 - Episode 24

Cristina and Meredith's surgical skills are put to the ultimate test.

Directors: Rob Corn
Now or Never

#3 - Now or Never 8.57

Season 5 - Episode 24

In the second part of the two hour season finale, George delivers stunning news to Bailey, sending shockwaves throughout the hospital, and Izzie's friends anxiously await her recovery from surgery. Meanwhile Bailey is surprisingly displeased after being accepted into the pediatric fellowship program, and the victim of a near-fatal traffic accident brings the talents of Seattle Grace's doctors together. This is the second hour of a 2-hour season finale.

Directors: Rob Corn
As We Know it

#4 - As We Know it 8.54

Season 2 - Episode 17

Derek is still operating when he finds out about Meredith's current situation. Meredith is freaking out about her situation. Webber and Bailey are dealing with medical health issues. Cristina and Izzie have their own issues to deal with because of Meredith's situation. Addison freaks out when George tries to find a solution to Bailey's impromtu postponement. Overall, Seattle Grace Hospital is still under code black and the situation is getting worse.

Directors: Peter Horton
It's the End of the World

#5 - It's the End of the World 8.53

Season 2 - Episode 16

An explosive case arrives at the O.R. that might endanger all the lives of the people working there, which leads Dr. Burke to declare a "Code Black" for the hospital. Bailey worries where her husband is as she is in labor. Also Izzie and Alex may be creating some heat.

Directors: Peter Horton
Sanctuary

#6 - Sanctuary 8.51

Season 6 - Episode 23

Seattle Grace Hospital is hit with a crisis like no other in its' history.

Directors: Stephen Cragg
Perfect Storm

#7 - Perfect Storm 8.46

Season 9 - Episode 24

Grey Sloan Memorial Hospital enters crisis mode as the storm rages, resources become scarce and patients flood in by the busload. Meanwhile, one of the doctors fights for their life.

Directors: Rob Corn
Fear (Of the Unknown)

#8 - Fear (Of the Unknown) 8.38

Season 10 - Episode 24

The doctors of Grey Sloan Memorial Hospital bid an emotional farewell to the beloved Cristina Yang. A possible act of terrorism rocks Seattle and causes chaos at the hospital. Meanwhile, Meredith makes a life changing decision and one doctor receives shocking news.

Directors: Tony Phelan
Suddenly

#9 - Suddenly 8.35

Season 8 - Episode 10

A severe car crash involving an entire family results in an all-hands-on situation in the ER, as the eldest daughter is left to make the toughest decision of her life. Meanwhile Teddy, still in the dark about Henry's death, calls upon Cristina to help with her patient in the O.R., and Lexie finds herself working alongside Mark's new girlfriend, Julia, during an eye surgery.

Directors: Ron Underwood
What a Difference a Day Makes

#10 - What a Difference a Day Makes 8.33

Season 5 - Episode 22

As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation ceremony, is admitted to the ER. Meanwhile, Izzie fears the worst when she begins experiencing familiar symptoms.

Directors: Rob Corn
Deterioration of the Fight or Flight Response (1)

#11 - Deterioration of the Fight or Flight Response (1) 8.32

Season 2 - Episode 26

Denny needs a heart or else. Izzie and George go crazy trying to get him one. Derek has the life of a friend in his hands as he operates on Burke who has been shot. Burke cannot operate on Denny after Denny's heart stopped and now Denny is in a dire condition. Cristina gets put in charge of the ER and she is worried about Burke.

Directors: Rob Corn
Freedom (2)

#12 - Freedom (2) 8.31

Season 4 - Episode 17

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

Directors: Rob Corn
Get Up, Stand Up

#13 - Get Up, Stand Up 8.31

Season 10 - Episode 12

On the day of April's wedding, the Grey Sloan Memorial doctors are all preoccupied with their own drama. Meredith and Cristina continue to argue about their research and careers, Bailey comes clean to Ben about her feelings regarding him moving back to Seattle, and Shane puts himself in a risky situation. Meanwhile, Derek gets a phone call that will change his life.

Directors: Tony Phelan
17 Seconds

#14 - 17 Seconds 8.29

Season 2 - Episode 25

George and Derek work together, Denny still doesn't have a heart, and Meredith gets paired with Callie. A 12-week pregnant girl dies in the O.R. and her parents try to keep the baby alive. This causes tension between Derek and Addison. One doctor's overreaction unites two bickering patients. Finn is still treating Doc for medical problems.

Directors: Dan Minahan
Drowning on Dry Land

#15 - Drowning on Dry Land 8.24

Season 3 - Episode 16

Almost everyone searches for Meredith while they ponder her place in the world. Addison considers pursuing Alex. Izzie takes desperate measures to manage the situation she is in. Someone ends up on the brink of death. Cristina and Burke have a blow-up fight about their announcement.

Directors: Rob Corn
Dark Was the Night

#16 - Dark Was the Night 8.21

Season 8 - Episode 9

Teddy puts her husband’s life in the hands of her peers when Henry is sent to the OR for surgery and she’s called away on another case; Meredith and Derek receive the long-awaited news about Zola; Callie and Jackson come under fire when their patient experiences post-surgery complications; and Meredith and Alex are involved in a life-threatening situation when they travel to a neighboring hospital to tend to a sick newborn, on Grey’s Anatomy

Directors: Allison Liddi-Brown
Didn't We Almost Have It All?

#17 - Didn't We Almost Have It All? 8.20

Season 3 - Episode 25

Callie and George make a big decision. A successor to Chief Webber is named. A man named Jeff Pope arrives. He is looking for his wife and newborn child. Cristina and Burke's wedding day has arrived and so have the interns first-year exam results.

Directors: Rob Corn
Flight

#18 - Flight 8.19

Season 8 - Episode 24

Faced with a life threatening situation, the doctors must fight to stay alive while trying to save the lives of their peers; Bailey and Ben make a decision regarding their relationship; and Teddy is presented with a tempting offer. Meanwhile, Richard plans a special dinner for the residents.

Directors: Rob Corn
Walk On Water

#19 - Walk On Water 8.18

Season 3 - Episode 15

The staff is trying to deal with antsy patients while dealing with a major disaster when a cargo ship strikes a Ferryboat in Seattle. The Chief must choose a team to go out on location and save what is left of the few lives spared.

Directors: Rob Corn
Into You Like a Train

#20 - Into You Like a Train 8.18

Season 2 - Episode 6

Train Wreck victims come to Seattle Grace and all staff gets called in. Everyone deals with really weird cases. Except Addison and Izzie. They work with a woman who is pregnant.

Directors: Jeff Melman
Some Kind of Miracle

#21 - Some Kind of Miracle 8.14

Season 3 - Episode 17

Everyone is pushing for Meredith to survive, or in this case to be revived. People are still dealing with the fallout from the ferry disaster. A young man named Lucas is having problems with brain-mouth coordination. Someone else dies.

Directors: Adam Arkin
Freedom (1)

#22 - Freedom (1) 8.13

Season 4 - Episode 16

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

Directors: Rob Corn
Transplant Wasteland

#23 - Transplant Wasteland 8.12

Season 9 - Episode 17

The discord and chaos created by the hospital's new management team causes one physician to question his future at Seattle Grace. Meanwhile, the doctors and the interns must juggle several transplant surgeries at once, each coming with its own set of obstacles.

Directors: Chandra Wilson
Ring of Fire

#24 - Ring of Fire 8.11

Season 13 - Episode 24

In the season finale, the doctors' lives are at risk after a dangerous patient escapes the hospital room. Alex must make a hard choice in his relationship with Jo while Meredith has some big news for Nathan that brings things to a turning point.

Directors: Debbie Allen
We Are Never Ever Getting Back Together

#25 - We Are Never Ever Getting Back Together 8.11

Season 10 - Episode 22

Cristina looks to Meredith for advice as she assesses her future at the hospital. Derek and Amelia work together on a difficult surgery involving conjoined twins. Meanwhile, Jo is spread too thin when she tries to work on several cases at once and Stephanie realizes the truth about Bailey’s bubble boy case.

Directors: Rob Corn